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| Status |
Public on Aug 09, 2023 |
| Title |
Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The objective of this study is to identify immunological differences between blood and liver in chronic hepatitis B (CHB) patients using Seq-well and 10x Chromium scRNAseq
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| Overall design |
Blood and liver FNAs were collected, and cellular and molecular capture were compared between the Seqwell S picowell-based and the 10x Chromium reverse-emulsion droplet based scRNAseq
This dataset represents SeqWell data only.
***Raw data for human samples not available due to patient privacy concerns***
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| Contributor(s) |
Genshaft AS, Subduhi S, Keo A, Sanchez Vasquez JD, Conceição-Neto N, Mahamed D, Boeijen LL, Alatrakchi N, Oetheimer C, Vilme M, Drake R, Fleming I, Tran N, Tzouanas C, Joseph-Chazan J, Arreola Villanueva M, van de Werken HJ, van Oord GW, Groothuismink ZM, Beudeker BJ, Osmani Z, Nkongolo S, Mehrotra A, Spittaels K, Feld J, Chung RT, de Knegt RJ, Janssen HL, Aerssens J, Bollekens J, Nacohen N, Lauer GM, Boonstra A, Shalek AK, Gehring AJ |
| Citation(s) |
37158243 |
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| Submission date |
Jun 06, 2023 |
| Last update date |
Oct 25, 2023 |
| Contact name |
Adam Gehring |
| E-mail(s) |
adam.gehring@uhnresearch.ca
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| Organization name |
UHN
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| Street address |
101 College St
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| City |
Toronto |
| State/province |
ON |
| ZIP/Postal code |
M5G 1L7 |
| Country |
Canada |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (32)
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| GSM7457952 |
blood, donor 10-1005 |
| GSM7457953 |
liver, donor 10-1006 |
| GSM7457954 |
blood, donor 10-1006 |
| GSM7457955 |
liver, donor 10-1007 |
| GSM7457956 |
blood, donor 10-1007 |
| GSM7457957 |
liver, donor 20-1002 |
| GSM7457958 |
blood, donor 20-1002 |
| GSM7457959 |
liver, donor 20-1003 |
| GSM7457960 |
blood, donor 20-1003 |
| GSM7457961 |
liver, donor 20-3001 |
| GSM7457962 |
blood, donor 20-3001 |
| GSM7457963 |
liver, donor 20-3002 |
| GSM7457964 |
blood, donor 20-3002 |
| GSM7457965 |
liver, donor 30-1021 |
| GSM7457966 |
blood, donor 30-1021 |
| GSM7457967 |
liver, donor 30-1022 |
| GSM7457968 |
blood, donor 30-1022 |
| GSM7457969 |
liver, donor 30-1023 |
| GSM7457970 |
blood, donor 30-1023 |
| GSM7457971 |
liver, donor 30-1024 |
| GSM7457972 |
blood, donor 30-1024 |
| GSM7457973 |
liver, donor 30-1025 |
| GSM7457974 |
blood, donor 30-1025 |
| GSM7457975 |
liver, donor 22-0002 |
| GSM7457976 |
blood, donor 22-0002 |
| GSM7457977 |
liver, donor 22-0004 |
| GSM7457978 |
blood, donor 22-0004 |
| GSM7457979 |
liver, donor 22-0010 |
| GSM7457980 |
blood, donor 22-0010 |
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| Relations |
| BioProject |
PRJNA980609 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE234241_Metadata.txt.gz |
371.5 Kb |
(ftp)(http) |
TXT |
| GSE234241_barcodes.tsv.gz |
353.2 Kb |
(ftp)(http) |
TSV |
| GSE234241_features.tsv.gz |
212.0 Kb |
(ftp)(http) |
TSV |
| GSE234241_matrix.mtx.gz |
365.8 Mb |
(ftp)(http) |
MTX |
| Raw data not provided for this record |
| Processed data are available on Series record |
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