|
| Status |
Public on May 25, 2023 |
| Title |
Effect of Domatinostat treatment on MKL1 cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the effect of HDAC inhibition, we treated MKL1 cells with 10µM of domatinostat or vehicle control (DMSO) for 24h, and carried out bulk RNA-seq
We then performed gene expression profiling analysis using data obtained from RNA-seq of vehicle control (DMSO treated) and domatinostat treated samples (in duplicates)
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| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for untreated and treated MKL1 cells.
|
| Web link |
https://www.sciencedirect.com/science/article/pii/S2666379123002203
|
| |
|
| Contributor(s) |
Gao L, Kannan A, Das B |
| Citation(s) |
37421947 |
| |
| Submission date |
May 25, 2023 |
| Last update date |
Aug 22, 2023 |
| Contact name |
Ling Gao |
| E-mail(s) |
ling.gao@va.gov, lingg3@hs.uci.edu
|
| Organization name |
Department of Veterans Affairs
|
| Street address |
5901 E.7th Street
|
| City |
Long Beach |
| State/province |
California |
| ZIP/Postal code |
90822 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
|
| Samples (4)
|
| GSM7428326 |
MKL1 cells treated with vehicle (DMSO) [MKL1_C1] |
| GSM7428327 |
MKL1 cells treated with vehicle (DMSO) [MKL1_C2] |
| GSM7428328 |
MKL1 cells treated with 10µM Domatinostat [MKL1_D1] |
| GSM7428329 |
MKL1 cells treated with 10µM Domatinostat [MKL1_D2] |
|
| Relations |
| BioProject |
PRJNA976292 |
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