|
| Status |
Public on Jun 12, 2023 |
| Title |
Metronomic administration of topotecan alone and in combination with docetaxel inhibits epithelial-mesenchymal transition in aggressive variant prostate cancers |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To identify molecular signatures and their potential to serve as novel biomarkers for monitoring treatment efficacy and disease progression response to treatment efficacy and disease progression
|
| |
|
| Overall design |
Effects of METRO-TOPO and CONV-TOPO exposure for six weeks on ARLow mCRPC/NEPC PC-3 tumor model (3D spheroid) were assessed using RNAseq.
|
| |
|
| Contributor(s) |
Mitra Ghosh T, Arnold RD, Mitra AK |
| Citation(s) |
37476073 |
| |
| Submission date |
May 24, 2023 |
| Last update date |
Sep 12, 2023 |
| Contact name |
Amit Kumar Mitra |
| E-mail(s) |
akm0060@auburn.edu
|
| Organization name |
AUBURN UNIVERSITY
|
| Department |
DRUG DISCOVERY AND DEVELOPMENT
|
| Lab |
Pharmacogenomics
|
| Street address |
HARRISON COLLEGE OF PHARMACY
|
| City |
AUBURN |
| State/province |
AL |
| ZIP/Postal code |
36849 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA975943 |
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