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| Status |
Public on Jan 15, 2024 |
| Title |
Transcriptome analysis of control and OTUD1 knockout SKOV3 Cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We have confirmed that high level of OTUD1 is important for retaining ovarian cancer stem cells (OCSCs) property. To investigate the exact mechanism of OTUD1 in the regulation of stemness maintain, we established SKOV3 cells with stable OTUD1 depletion by using sgRNA.
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| Overall design |
RNA-seq was performed in SKOV3-sgNC and SKOV3-sgOTUD1 cells with 3 replicates. Gene expression profiling was analyzed according to the sequencing results.
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| Contributor(s) |
Chen Y, Qiang Y, Zhang W, Li F |
| Citation(s) |
38351029 |
| |
| Submission date |
May 18, 2023 |
| Last update date |
Feb 26, 2024 |
| Contact name |
Yurou Chen |
| E-mail(s) |
yurouchen1991@whu.edu.cn
|
| Organization name |
Zhongnan Hospital of Wuhan University
|
| Street address |
Donghu Road
|
| City |
Wuhan |
| ZIP/Postal code |
430071 |
| Country |
China |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA973961 |
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