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| Status |
Public on Jul 07, 2024 |
| Title |
Macrophage containing multicellular lung organoids [scRNA-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Proper lung development and function maintenance depend on the cross-talk between resident immune cell populations and lung epithelial cells. However, understanding the underlying cellular and molecular mechanisms are difficult to study in human. Here, we present a method to develop macrophage-containing alveolar organoids from human pluripotent stem cells to investigate reciprocal interactions between alveolar macrophages and epithelial cells in lung development.
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| Overall design |
Alveolar organoids were cultured without or with macrophages and analyzed using scRNAseq.
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| Contributor(s) |
Lee MO, Kim J |
| Citation missing |
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| |
| Submission date |
May 02, 2023 |
| Last update date |
Jul 08, 2024 |
| Contact name |
Dayeon Gil |
| E-mail(s) |
gilje@korea.kr
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| Phone |
+82-43-249-2527
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| Organization name |
Korea national institute of health
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| Department |
Division of intractable disease research
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| Street address |
202 Osongsaengmyung 2-ro, Heungdeok-gu
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| City |
Cheongju-si |
| State/province |
Chungcheongbuk-do |
| ZIP/Postal code |
28160 |
| Country |
South Korea |
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| Platforms (1) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE231468 |
Macrophage containing multicellular lung organoids |
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| Relations |
| BioProject |
PRJNA966111 |
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