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| Status |
Public on Sep 18, 2024 |
| Title |
Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy [kdSdc1_RNAseq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate the function of SDC1 in the regulation of anti-tumor immunity, we established B16 cell lines in which sdc1 or control RNA has been knocked down by shRNA. Then the cells were stimulated with or without IFNγ. We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different groups, each group included three replicates.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for ShRFP control or Shsdc1 B16 cells with or without IFNr stimulation.
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| Contributor(s) |
Liu Y, Xu C, Li Z, Xu G, Yang Z, Xiang L, Jiao K, Chen Z, Zuo Y, Liu Y |
| Citation(s) |
39259785 |
| |
| Submission date |
Apr 30, 2023 |
| Last update date |
Sep 18, 2024 |
| Contact name |
Yun Liu |
| E-mail(s) |
liuyun29@shsci.org
|
| Organization name |
Shanghai Cancer Institute
|
| Street address |
No. 2200, Xietu Road, Xuhui District, Shanghai, China
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| City |
Shanghai |
| ZIP/Postal code |
200000 |
| Country |
China |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE231357 |
Syndecan-1 inhibition promotes anti-tumor immune response and facilitates the efficacy of anti-PD1 checkpoint immunotherapy |
|
| Relations |
| BioProject |
PRJNA964464 |
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