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| Status |
Public on Apr 15, 2024 |
| Title |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Expression profiling by high throughput sequencing
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
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| Overall design |
Refer to individual Series
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| Web link |
http://10.1016/j.stem.2024.03.013
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| Citation(s) |
38626772 |
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| Submission date |
Apr 25, 2023 |
| Last update date |
Jul 15, 2024 |
| Contact name |
Osama Al Dalahmah |
| E-mail(s) |
oa2298@cumc.columbia.edu
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| Organization name |
Columbia University Irving Medical Center
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| Department |
Pathology & Cell Biology
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| Street address |
622 West 168th Street
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| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10032 |
| Country |
USA |
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| Platforms (2) |
| GPL17930 |
[HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [HuGene20stv1_Hs_ENTREZG_17.0.0] |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (61)
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| GSM7223948 |
post-mortem brain tissue, Ctrl-4 |
| GSM7223949 |
post-mortem brain tissue, FTD-1 |
| GSM7223950 |
post-mortem brain tissue, FTD-2 |
| GSM7223951 |
post-mortem brain tissue, FTD-3 |
| GSM7223952 |
post-mortem brain tissue, FTD-4 |
| GSM7223953 |
post-mortem brain tissue, FTD-5 |
| GSM7223954 |
post-mortem brain tissue, FTD-6 |
| GSM7223955 |
post-mortem brain tissue, FTD-7 |
| GSM7223956 |
post-mortem brain tissue, FTD-8 |
| GSM7223957 |
iPSC derived neurons, Ctrl_A |
| GSM7223958 |
iPSC derived neurons, Ctrl_B |
| GSM7223959 |
iPSC derived neurons, Ctrl_C |
| GSM7223960 |
iPSC derived neurons, FTD_A |
| GSM7223961 |
iPSC derived neurons, FTD_B |
| GSM7223962 |
iPSC derived neurons, FTD_C |
| GSM7224009 |
iPSC neurons, CtrlSPP1-1 |
| GSM7224010 |
iPSC neurons, CtrlSPP1-2 |
| GSM7224011 |
iPSC neurons, CtrlSPP1-3 |
| GSM7224012 |
iPSC neurons, CtrlSPP1-4 |
| GSM7224013 |
iPSC neurons, CtrlGFP-1 |
| GSM7224014 |
iPSC neurons, CtrlGFP-2 |
| GSM7224015 |
iPSC neurons, CtrlGFP-3 |
| GSM7224016 |
iPSC neurons, CtrlGFP-4 |
| GSM7224017 |
iPSC neurons, FTDshSPP1-1 |
| GSM7224018 |
iPSC neurons, FTDshSPP1-2 |
| GSM7224019 |
iPSC neurons, FTDshSPP1-3 |
| GSM7224020 |
iPSC neurons, FTDshSPP1-4 |
| GSM7224021 |
iPSC neurons, FTDscr-1 |
| GSM7224022 |
iPSC neurons, FTDscr-2 |
| GSM7224023 |
iPSC neurons, FTDscr-3 |
| GSM7224024 |
iPSC neurons, FTDscr-4 |
| GSM7224025 |
iPSC neurons, FTDvehicle-1 |
| GSM7224026 |
iPSC neurons, FTDvehicle-2 |
| GSM7224027 |
iPSC neurons, FTDvehicle-3 |
| GSM7224028 |
iPSC neurons, FTDmetformin-1 |
| GSM7224029 |
iPSC neurons, FTDmetformin-2 |
| GSM7224030 |
iPSC neurons, FTDmetformin-3 |
| GSM7225754 |
Postmortem human brain, FTD, HO001 |
| GSM7225755 |
Postmortem human brain, FTD, GO004 |
| GSM7225756 |
Postmortem human brain, FTD, GO006 |
| GSM7225757 |
Postmortem human brain, FTD, HO008 |
| GSM7225758 |
Postmortem human brain, FTD, HO010 |
| GSM7225759 |
Postmortem human brain, FTD, HO012 |
| GSM7225760 |
Postmortem human brain, Ctrl , HO002 |
| GSM7225761 |
Postmortem human brain, Ctrl , GO003 |
| GSM7225762 |
Postmortem human brain, Ctrl , GO005 |
| GSM7225763 |
Postmortem human brain, Ctrl , HO007 |
| GSM7225764 |
Postmortem human brain, Ctrl , HO009 |
| GSM7225765 |
Postmortem human brain, Ctrl , HO011 |
| GSM7225766 |
Postmortem human brain, Ctrl , HO013 |
| GSM7225767 |
iPSC-derived neural graft, Ctrl , GF010 |
| GSM7225768 |
iPSC-derived neural graft, Ctrl , GF012 |
| GSM7225769 |
iPSC-derived neural graft, Ctrl , GF014 |
| GSM7225770 |
iPSC-derived neural graft, Ctrl , GF016 |
| GSM7225771 |
iPSC-derived neural graft, FTD, GF011 |
| GSM7225772 |
iPSC-derived neural graft, FTD, GF013 |
| GSM7225773 |
iPSC-derived neural graft, FTD, GF015 |
| GSM7225774 |
iPSC-derived neural graft, FTD, GF017 |
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| This SuperSeries is composed of the following SubSeries: |
| GSE230447 |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons |
| GSE230450 |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons |
| GSE230519 |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons |
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| Relations |
| BioProject |
PRJNA961691 |
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