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| Status |
Public on Jul 01, 2023 |
| Title |
Prior antibiotic administration disrupts outcomes of PD-1 blockade in advanced gastric cancer by altering gut microbiome and systemic immune response |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Other
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| Summary |
We thoroughly uncovered clinical and translational evidence that pATB use can influence treatment outcomes of ICI treatment, highlighting the significance of such practice among patients with AGC.
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| Overall design |
We analyzed circulating immune cells and gut microbiota via single-cell (sc) RNA and TCR sequencing
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| Contributor(s) |
Kim C, Koh J, Shin S, Shin J, Jeung H, Lee J, Nam Y, Jung M |
| Citation(s) |
37890486 |
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| Submission date |
Apr 11, 2023 |
| Last update date |
Nov 01, 2023 |
| Contact name |
June-Young Koh |
| E-mail(s) |
kohjy2000@gmail.com
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| Phone |
82-1027076371
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| Organization name |
GENOME INSIGHT
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| Street address |
2575 Nambusunhwan-ro,
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| City |
Seocho-gu |
| State/province |
Seoul |
| ZIP/Postal code |
06735 |
| Country |
South Korea |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA954318 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE229379_RAW.tar |
253.9 Mb |
(http)(custom) |
TAR (of CSV, H5) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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