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Series GSE228394 Query DataSets for GSE228394
Status Public on Feb 09, 2024
Title Characterization of stress-susceptible cells and gene in mouse brain via Spatial Transcriptomics
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Spatial transcriptome analysis of brain sections from non-stressed controls (CON), susceptible mice (SUS) and resistant mice (RES) was performed to investigate spatial patterns of gene expression in multiple brain regions to gain new insights into stress susceptibility.
Overall design Animals were subjected to 10 days of chronic social defeat stress and then phenotypes were acquired using social interaction tests.Fresh brain tissue was collected 1.5 hours after the last CSDS exposure of mice, and we obtained three coronal sections(Bregma2.0~2.1) from the left brain of Control, susceptible, resilient mouse by cryosections of mouse brains. After that Spatial transcriptome (ST) sequencing was performed.
Contributor(s) Wang T, Song Z, Wu H
Citation(s) 38264685
Submission date Mar 28, 2023
Last update date Feb 10, 2024
Contact name TING WANG
Organization name Beijing Institute of Basic Medical Sciences
Street address Haidian District, Beijing
City Beijing
ZIP/Postal code 100850
Country China
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (3)
GSM7120222 Control
GSM7120223 Resilient
GSM7120224 Susceptible
BioProject PRJNA949622

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE228394_RAW.tar 173.5 Mb (http)(custom) TAR (of TAR)
GSE228394_metadata.csv.gz 341.7 Kb (ftp)(http) CSV
GSE228394_tissue_image.tar.gz 1.4 Mb (ftp)(http) TAR
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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