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Series GSE22578 Query DataSets for GSE22578
Status Public on Jun 24, 2011
Title Wilms Tumor-1 (WT-1) and its candidate target genes in gliomagenesis
Organism Homo sapiens
Experiment type Expression profiling by array
Summary WT-1 is a zinc-finger transcription factor with important roles during development. WT-1 is associated with the development of tumors of varied origins.
Our lab has previously demonstrated aberrant expression of WT-1 in tumor cells. Necessity of WT-1 for tumor cell growth- in vitro & in vivo- was also shown.
Overall design Human glioma U251 cells were treated with Oligofectamine (CTRL), Oligofectamine + non-targeting siRNA control (SCR) or Oligofectamine+ si-WT1 siRNA (Si). Biological triplicates were run on microarrays.
Contributor(s) Broaddus WC, Fillmore H, Dumur CI, Chidambaram A
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Submission date Jun 25, 2010
Last update date Dec 06, 2018
Contact name William C Broaddus
Organization name VCU
Department Neurosurgery
Street address 417 North 11th Street, Sixth floor
City Richmond
State/province VA
ZIP/Postal code 23298
Country USA
Platforms (1)
GPL571 [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array
Samples (9)
GSM560320 U251si_1
GSM560321 U251scr_1
GSM560322 U251ctrl_1
BioProject PRJNA128411

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Supplementary file Size Download File type/resource
GSE22578_RAW.tar 29.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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