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| Status |
Public on Jun 24, 2011 |
| Title |
Wilms Tumor-1 (WT-1) and its candidate target genes in gliomagenesis |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
WT-1 is a zinc-finger transcription factor with important roles during development. WT-1 is associated with the development of tumors of varied origins.
Our lab has previously demonstrated aberrant expression of WT-1 in tumor cells. Necessity of WT-1 for tumor cell growth- in vitro & in vivo- was also shown.
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| Overall design |
Human glioma U251 cells were treated with Oligofectamine (CTRL), Oligofectamine + non-targeting siRNA control (SCR) or Oligofectamine+ si-WT1 siRNA (Si). Biological triplicates were run on microarrays.
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| Contributor(s) |
Broaddus WC, Fillmore H, Dumur CI, Chidambaram A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 25, 2010 |
| Last update date |
Dec 06, 2018 |
| Contact name |
William C Broaddus |
| Organization name |
VCU
|
| Department |
Neurosurgery
|
| Street address |
417 North 11th Street, Sixth floor
|
| City |
Richmond |
| State/province |
VA |
| ZIP/Postal code |
23298 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA128411 |
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