|
| Status |
Public on Sep 30, 2024 |
| Title |
Effects of the conditioned medium derived from human adipose-derived mesenchymal stem cells (hAdMSC-CM) on Benzalkonium Chloride (BAC)-treated human corneal epithelial cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the mechanism underlying effects of hAdMSC-CM on BAC-induced cytotoxicity, inflammation, and barrier dysfunction in human corneal epithelial cells.
We confirmed that the the effects of hAdMSC-CM were associated with the TGFβ and JAK-STAT signalling pathways.
|
| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for BAC-treated human corneal epithelial cells with or without hAdMSCs-CM.
|
| |
|
| Contributor(s) |
Imaizumi T, Hayashi R |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 15, 2023 |
| Last update date |
Sep 30, 2024 |
| Contact name |
Tsutomu Imaizumi |
| E-mail(s) |
imaizumit@rohto.co.jp
|
| Phone |
818099448647
|
| Organization name |
Rohto Pharmaceutical Co., Ltd
|
| Department |
Basic Research Development Division
|
| Street address |
6-5-4 Kunimidai
|
| City |
Kizugawa |
| State/province |
Kyoto |
| ZIP/Postal code |
619-0216 |
| Country |
Japan |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (6)
|
| GSM7048127 |
Human corneal epithelial cells, Treatment of BAC 1 |
| GSM7048128 |
Human corneal epithelial cells, Treatment of BAC 2 |
| GSM7048129 |
Human corneal epithelial cells, Treatment of BAC 3 |
| GSM7048130 |
Human corneal epithelial cells, Treatment of BAC and hAdMSC-CM 1 |
| GSM7048131 |
Human corneal epithelial cells, Treatment of BAC and hAdMSC-CM 2 |
| GSM7048132 |
Human corneal epithelial cells, Treatment of BAC and hAdMSC-CM 3 |
|
| Relations |
| BioProject |
PRJNA935413 |
Less...
More...