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| Status |
Public on Dec 31, 2012 |
| Title |
Rhabdomyosarcoma cells (SJRH30) response to hypoxia: time course |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Under hypoxic condition, solid tumor cells are known to involve gene expressions for adopting low O2 condition. We examined chronic hypoxia environment of human rhabdomyosarcoma cell (SJRH30), which is important for understanding characteristic of cancer in the body.
We used microarrays to detail time development of gene expression by using new gene-set analysis called GSMTA and identified up/down-regulated gene sets during hypoxic stress.
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| Overall design |
We measured gene expressions at four time-points during 24 hours (0h, 6h, 12h and 24h) under 1% hypoxic condition by Affymetrix GeneChip. GSMTA identified novel differentially-expressed gene set under hypoxic stress at each time point.
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| Contributor(s) |
Oshiro S, Ogishima S |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 21, 2010 |
| Last update date |
Dec 06, 2018 |
| Contact name |
Soichi Ogishima |
| E-mail(s) |
ogishima@sysbioevo.org
|
| Phone |
+81 (0)3 5803 4762
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| Fax |
+81 (0)3 5803 0247
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| Organization name |
Tokyo Medical and Dental University
|
| Department |
Medical Research Institute
|
| Lab |
Dept. of Bioinformatics
|
| Street address |
Yushima 1-5-45
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| City |
Bunkyo-ku |
| State/province |
Tokyo |
| ZIP/Postal code |
113 8510 |
| Country |
Japan |
| |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (8)
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| GSM558109 |
SJRH30 cells at time 0h, biological rep1 |
| GSM558110 |
SJRH30 cells at time 0h, biological rep2 |
| GSM558111 |
SJRH30 cells at time 6h, biological rep1 |
| GSM558112 |
SJRH30 cells at time 6h, biological rep2 |
| GSM558113 |
SJRH30 cells at time 12h, biological rep1 |
| GSM558114 |
SJRH30 cells at time 12h, biological rep2 |
| GSM558115 |
SJRH30 cells at time 24h, biological rep1 |
| GSM558116 |
SJRH30 cells at time 24h, biological rep2 |
|
| Relations |
| BioProject |
PRJNA128619 |
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