|
| Status |
Public on May 31, 2024 |
| Title |
ST105-02: Deciphering and comparison of tumor mutational burden of MBT2 and LM8 mouse cancer cell lines |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The aim of this project is to use high-throughput transcriptomic approach to decipher the tumor mutational burden (TMB) of two cancer cell lines, MBT2 (urothelial) and LM8 (osteosarcoma), syngeneic of the C3H/HeN mouse strain, and to compare them as biomarker of immunogenicity (Rizvi NA et al. Science, 2015, Sha D et al. Cancer Discovery, 2020).
|
| |
|
| Overall design |
The two cell lines MBT2 and LM8 have been grown in-vitro and harvested without any supplemental treatment for RNA extraction in duplicate.
|
| |
|
| Contributor(s) |
Thierry S, Boucard-Jourdin M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Feb 06, 2023 |
| Last update date |
May 31, 2024 |
| Contact name |
joel lachuer |
| E-mail(s) |
lachuer@univ-lyon1.fr
|
| Phone |
+33 664035058
|
| Organization name |
university Lyon1
|
| Lab |
Profilexpert platform
|
| Street address |
8 avenue rockefeller
|
| City |
Lyon |
| ZIP/Postal code |
69008 |
| Country |
France |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (4)
|
|
| Relations |
| BioProject |
PRJNA931992 |
Less...
More...