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| Status |
Public on Jan 30, 2023 |
| Title |
Insights into the evolution of dermal armour: osteoderms in a mammal, the spiny mouse |
| Organism |
Acomys cahirinus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The goals of this study are to compare NGS-derived transcriptomes (RNA-Seq) derived from skin sampled from the distal and the proximal regions. Using Acomys cahirinus we describe the structure and development of osteoderms in the tail which develop in a proximal to distal and dorsal to ventral sequence over a 6-week period postnatally. We use RNA sequencing to identify which gene regulatory networks are involved in their development which together suggests a deep molecular homology exists in the mammalian dermis which can be activated at any time in evolution.
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| Overall design |
RNA was isolated from the distal and proximal regions of 6 newborn Acomys pups. The RNA was used in the construction of Illumina paired-end RNA-SEQ libraries, which were sequenced on the Illumina NovaSeq6000 platform.
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| Contributor(s) |
Bradley BW, Trey P, Maden M |
| Citation missing |
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| |
| Submission date |
Jan 29, 2023 |
| Last update date |
Jan 30, 2023 |
| Contact name |
William Bradley Barbazuk |
| E-mail(s) |
bbarbazuk@ufl.edu
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| Phone |
352-273-8624
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| Organization name |
University of Florida
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| Department |
Biology
|
| Street address |
UF-CGRC Room 407 2033 Mowry Rd
|
| City |
Gainesville |
| State/province |
Florida |
| ZIP/Postal code |
32610 |
| Country |
USA |
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| Platforms (1) |
| GPL29848 |
Illumina NovaSeq 6000 (Acomys cahirinus) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA929296 |
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