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| Status |
Public on Apr 27, 2023 |
| Title |
Salivary gland cancer organoids are valid for preclinical genotype-oriented medical precision trials |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We established patient-derived organoids and monolayer culture cells from the salivary gland cancer cases. To compare the RNA profiles of primary culture cells (Organoids and monolayer culture cells) and their parental tumors, we isolated total RNA from 2 cases of the salivary gland cancer and performed transcriptome sequencing for the organoids, monolayer culture cells, and their parental tumors of both cases. Case 6 is a case of adenoid cystic carcinoma and Case 11 is a case of salivary duct carcinoma.
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| |
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| Overall design |
Comparative gene expression profiling analysis of the primary tumor, the organoids, and the monolayer culture cells from cases 6 and 11.
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| Web link |
https://doi.org/10.1016/j.isci.2023.106695
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| |
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| Contributor(s) |
Ishikawa T, Furukawa T |
| Citation(s) |
37207275 |
| |
| Submission date |
Jan 23, 2023 |
| Last update date |
Jul 28, 2023 |
| Contact name |
Tomohiko Ishikawa |
| E-mail(s) |
tomish1988@gmail.com
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| Organization name |
Tohoku University Graduate School of Medicine
|
| Department |
Otolaryngology - Head and Neck Surgery
|
| Street address |
1-1 Seiryo-machi, Aoba-ku
|
| City |
Sendai |
| State/province |
Miyagi |
| ZIP/Postal code |
980-8574 |
| Country |
Japan |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA926693 |
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