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| Status |
Public on Aug 16, 2024 |
| Title |
Assessment of ‘molecular organ age’ in pre-transplant kidney biopsies |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Clinical kidney biopsies variably contain cortex and medulla depending on biopsy depth and angle. Therefore, biopsy composition may alter the transcriptional profile and confound conclusions drawn from differential gene expression analysis. To account for this in retrieval biopsies, we assessed differences in gene expression between paired cortex and medulla samples in n=5 human kidneys.
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data kidney biopsies taken from cortex and medulla
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| Contributor(s) |
Zhang R, Trotter PB, McCaffrey J, Stewart BJ, Ferdinand JR, Loudon KW, Riding A, West J, Ferro A, Kirkpatrick R, Clatworthy MR |
| Citation(s) |
38692408 |
| |
| Submission date |
Jan 13, 2023 |
| Last update date |
Aug 16, 2024 |
| Contact name |
Roy Zhang |
| Organization name |
MRC Laboratory of Molecular Biology
|
| Street address |
Cambridge Biomedical Campus, Francis Crick Ave
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| City |
Cambridge |
| ZIP/Postal code |
CB2 0QH |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (9)
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| Relations |
| BioProject |
PRJNA923683 |
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