|
| Status |
Public on Jan 10, 2024 |
| Title |
Metabolic targeting as a strategy to overcome targeted therapy resistance in NRAS-mutated melanoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We used single cell RNA sequencing (scRNA-seq) to analyze the molecular response of melanoma xenografts to combined MEK-inhibitng and metabolic targeting therapy.
|
| |
|
| Overall design |
Patient-derived melanoma cell cultures were injected into the flank of Balb-c/nude mice. The xenografts of the different treatment groups were analyzed using scRNAseq.
|
| |
|
| Contributor(s) |
Eichhoff O, Balázs Z, Levesque MP |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 05, 2023 |
| Last update date |
Jan 10, 2024 |
| Contact name |
Zsolt Balázs |
| E-mail(s) |
dzsidipi@gmail.com
|
| Organization name |
University of Zurich
|
| Street address |
Schmelzbergstrasse 26
|
| City |
Zurich |
| ZIP/Postal code |
8006 |
| Country |
Switzerland |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA918697 |
Less...
More...