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| Status |
Public on Jan 05, 2023 |
| Title |
single-nucleus RNA-seq of microvessel-enriched vascular cells and corresponding parenchyma from frontal cortex samples |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Vascular cell types are under-represented in standard single-nucleus RNA-Seq studies of human frozen post-mortem brain tissue. Using a novel microvessel-enrichment procedure allows to obtain highly purified fractions of vascular cell types and their corresponding parenchymal fraction of the same post-mortem brain tissue sample.
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| Overall design |
Vascular and parenchymal fractions of post-mortem frontal cortex samples were obtained from 10 control and 10 Alzheimer's disease patients, resulting in a total of 40 samples subjected to single-nucleus RNA-seq (10X Genomics)
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| Contributor(s) |
Sleven H, Cader Z, Webber C, Ansorge O, Wessely F |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jan 02, 2023 |
| Last update date |
Jan 07, 2023 |
| Contact name |
Frank Wessely |
| Organization name |
Cardiff University
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| Department |
UK DRI
|
| Street address |
Maindy Road
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| City |
Cardiff |
| ZIP/Postal code |
CF24 4HQ |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (40)
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| Relations |
| BioProject |
PRJNA917304 |
| SRA |
SRP415453 |
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