|
| Status |
Public on Nov 22, 2023 |
| Title |
Mutant p53R211* specifically suppresses Th17 cell population and ameliorates the arthritic condition in AIA rat via direct binding of TBK1 and inhibition of TBK1-IRF3-STING signaling cascade |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In vivo studies were investigated using rat p53R211* overexpressing adjuvant-induced arthritis (AIA) rat model established by adeno-associated virus (AAV) injection.
|
| |
|
| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for P53R211* in AIA rats.
|
| |
|
| Contributor(s) |
Zeng Y, Wong VK |
| Citation(s) |
37935918 |
| |
| Submission date |
Dec 16, 2022 |
| Last update date |
Nov 23, 2023 |
| Contact name |
Yaling Zeng |
| E-mail(s) |
ZeroZENGYL@outlook.com
|
| Organization name |
Macau university of science and technology
|
| Street address |
Avenida Wai Long, Taipa, Macau, China Avenida Wai Long, Taipa, Macau, China
|
| City |
Macau |
| ZIP/Postal code |
999078 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA913129 |
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