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| Status |
Public on Dec 03, 2022 |
| Title |
Smurfness-based two-phase model of ageing helps deconvolve the ageing transcriptional signature [RNA-seq] |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Gene expression changes characterization in whole body Drosophila melanogaster mated females as a function of chronological age and Smurf status
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data of Drosophila Drs-GFP line. Smurf and non-Smurf Individuals are sampled at three different time points (20 days – 90% survival, 30 days – 50% survival, 40 days – 10% survival), for a total of 32 samples (16 Smurfs and 16 non-Smurfs). Smurfs are sampled at a different time after transition (unknown time -Mixed samples, within 5 hours from transition – 5h, within 24h from transition -1d). In non – Smurfs, the “time after transition” indicates that the flies were sampled at the same moment of the corresponding Smurfs. Comparisons are made to study the Smurf transcriptome and chronological age-related changes.
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| Contributor(s) |
Zane F, Bouzid H, Besse S, Marmol SS, Molina JL, Cansell C, Aprahamian F, Durand S, Ayache J, Antoniewski C, Rera M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Nov 30, 2022 |
| Last update date |
Dec 03, 2022 |
| Contact name |
Michael Rera |
| E-mail(s) |
michael.rera@cri-paris.org
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| Phone |
0781945974
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| Organization name |
UTELife lab
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| Lab |
UTELife
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| Street address |
8bis Rue Charles V, Center for Research and Interdisciplinarity
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| City |
Paris |
| State/province |
- None - |
| ZIP/Postal code |
75004 |
| Country |
France |
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| Platforms (1) |
| GPL21306 |
Illumina HiSeq 4000 (Drosophila melanogaster) |
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| Samples (32)
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| GSM6766936 |
32 days, Smurf, Mixed [32sM_10] |
| GSM6766937 |
40 days, non-Smurf, Mixed [40nM_13] |
| GSM6766938 |
40 days, Smurf, Mixed [40sM_16] |
| GSM6766939 |
20 days, non-Smurf, 1day [20n1d_a] |
| GSM6766940 |
20 days, non-Smurf, 1day [20n1d_b] |
| GSM6766941 |
20 days, non-Smurf, 1day [20n1d_c] |
| GSM6766942 |
30 days, non-Smurf, 5hours [30n5h_c1] |
| GSM6766943 |
30 days, non-Smurf, 5hours [30n5h_c2] |
| GSM6766944 |
30 days, Smurf, 5hours [30s5h_c3] |
| GSM6766945 |
30 days, Smurf, 5hours [30s5h_c4] |
| GSM6766946 |
40 days, non-Smurf, 5hours [40n5h_c5] |
| GSM6766947 |
40 days, non-Smurf, 5hours [40n5h_c6] |
| GSM6766948 |
40 days, Smurf, 5hours [40s5h_c7] |
| GSM6766949 |
40 days, Smurf, 5hours [40s5h_c8] |
| GSM6766950 |
20 days, Smurf, 1day [20s1d_d] |
| GSM6766951 |
20 days, Smurf, 1day [20s1d_e] |
| GSM6766952 |
20 days, Smurf, 1day [20s1d_f] |
| GSM6766953 |
30 days, non-Smurf, 1day [30n1d_g] |
| GSM6766954 |
30 days, non-Smurf, 1day [30n1d_h] |
| GSM6766955 |
30 days, non-Smurf, 1day [30n1d_i] |
| GSM6766956 |
30 days, Smurf, 1day [30s1d_j] |
| GSM6766957 |
30 days, Smurf, 1day [30s1d_k] |
| GSM6766958 |
30 days, Smurf, 1day [30s1d_l] |
| GSM6766959 |
40 days, non-Smurf, 1day [40n1d_m] |
| GSM6766960 |
40 days, non-Smurf, 1day [40n1d_n] |
| GSM6766961 |
40 days, non-Smurf, 1day [40n1d_o] |
| GSM6766962 |
40 days, Smurf, 1day [40s1d_p] |
| GSM6766963 |
40 days, Smurf, 1day [40s1d_q] |
| GSM6766964 |
40 days, Smurf, 1day [40s1d_r] |
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| Relations |
| BioProject |
PRJNA906973 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE219063_RNAseq_raw_data_counts_matrix.tabular.txt.gz |
711.3 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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