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| Status |
Public on Nov 18, 2023 |
| Title |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Other
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| Summary |
This SuperSeries is composed of the SubSeries listed below.
The main processed data are organized in the following two Figshare links:
Seurat objects: https://doi.org/10.6084/m9.figshare.23290004
ReDeeM-V output: https://doi.org/10.6084/m9.figshare.24418966.v1
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| Overall design |
Refer to individual Series
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| Citation(s) |
38253266 |
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| Submission date |
Nov 29, 2022 |
| Last update date |
Jun 04, 2024 |
| Contact name |
Chen Weng |
| E-mail(s) |
cweng@wi.mit.edu
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| Organization name |
Broad Institute and Whitehead Institute
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| Department |
Genetics
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| Lab |
Vijay Sankaran lab and Jonathan Weissman lab
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| Street address |
415 Main St, Cambridge
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| City |
Boston |
| State/province |
OH |
| ZIP/Postal code |
02139 |
| Country |
USA |
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| Platforms (2) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (56)
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| GSM6764995 |
Donor Aged1, BMMCs, mRNA-derived cDNA, sample 10 |
| GSM6764996 |
Donor Aged1, BMMCs, ATAC, sample 10 |
| GSM6764997 |
Donor Aged1, BMMCs, mitochondrial DNA , sample 10 |
| GSM6764998 |
Donor Aged1, HSPC or CD34 enriched cells from BMMC, mRNA-derived cDNA, sample 11 |
| GSM6764999 |
Donor Aged1, HSPC or CD34 enriched cells from BMMC, ATAC, sample 11 |
| GSM6765000 |
Donor Aged1, HSPC or CD34 enriched cells from BMMC, mitochondrial DNA, sample 11 |
| GSM6766855 |
Donor Aged2, BMMCs, mRNA-derived cDNA, sample 12 |
| GSM6766856 |
Donor Aged2, BMMCs, ATAC, sample 12 |
| GSM6766857 |
Donor Aged2, BMMCs, mitochondrial DNA , sample 12 |
| GSM6766858 |
Donor Aged2, HSPC or CD34 enriched cells from BMMC, mRNA-derived cDNA, sample 13 |
| GSM6766859 |
Donor Aged2, HSPC or CD34 enriched cells from BMMC, ATAC, sample 13 |
| GSM6766860 |
Donor Aged2, HSPC or CD34 enriched cells from BMMC, mitochondrial DNA, sample 13 |
| GSM6771599 |
Donor Young-1, BMMCs, mRNA-derived cDNA, sample 1 |
| GSM6771600 |
Donor Young-1, BMMCs, ATAC, sample 1 |
| GSM6771601 |
Donor Young-1, BMMCs, mitochondrial DNA , sample 1 |
| GSM6771602 |
Donor Young-1, HSPC or CD34 enriched cells from BMMC, mRNA-derived cDNA, sample 2 |
| GSM6771603 |
Donor Young-1, HSPC or CD34 enriched cells from BMMC, ATAC, sample 2 |
| GSM6771604 |
Donor Young-1, HSPC or CD34 enriched cells from BMMC, mitochondrial DNA, sample 2 |
| GSM6771605 |
Donor Young-1, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mRNA-derived cDNA, sample 3 |
| GSM6771606 |
Donor Young-1, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, ATAC, sample 3 |
| GSM6771607 |
Donor Young-1, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mitochondrial DNA, sample 3 |
| GSM6774908 |
Donor Young-1, Timepoint2, BMMCs, mRNA-derived cDNA, sample 4 |
| GSM6774909 |
Donor Young-1, Timepoint2, BMMCs, ATAC, sample 4 |
| GSM6774910 |
Donor Young-1, Timepoint2, BMMCs, mitochondrial DNA , sample 4 |
| GSM6774911 |
Donor Young-1, Timepoint2, HSPC or CD34 enriched cells from BMMC, mRNA-derived cDNA, sample 5 |
| GSM6774912 |
Donor Young-1, Timepoint2, HSPC or CD34 enriched cells from BMMC, ATAC, sample 5 |
| GSM6774913 |
Donor Young-1, Timepoint2, HSPC or CD34 enriched cells from BMMC, mitochondrial DNA, sample 5 |
| GSM6774914 |
Donor Young-1, Timepoint2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mRNA-derived cDNA, sample 6 |
| GSM6774915 |
Donor Young-1, Timepoint2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, ATAC, sample 6 |
| GSM6774916 |
Donor Young-1, Timepoint2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mitochondrial DNA, sample 6 |
| GSM6779130 |
Donor Young-2, BMMCs, mRNA-derived cDNA, sample 7 |
| GSM6779131 |
Donor Young-2, BMMCs, ATAC, sample 7 |
| GSM6779132 |
Donor Young-2, BMMCs, mitochondrial DNA , sample 7 |
| GSM6779133 |
Donor Young-2, HSPC or CD34 enriched cells from BMMC, mRNA-derived cDNA, sample 8 |
| GSM6779134 |
Donor Young-2, HSPC or CD34 enriched cells from BMMC, ATAC, sample 8 |
| GSM6779135 |
Donor Young-2, HSPC or CD34 enriched cells from BMMC, mitochondrial DNA, sample 8 |
| GSM6779136 |
Donor Young-2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mRNA-derived cDNA, sample 9 |
| GSM6779137 |
Donor Young-2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, ATAC, sample 9 |
| GSM6779138 |
Donor Young-2, HSC or CD34+CD45RA-CD90+ enriched cells from BMMC, mitochondrial DNA, sample 9 |
| GSM8113080 |
Crispr Mouse with ReDeeM, Batch1, ATAC (enriched mito included), sample 14 |
| GSM8113081 |
Crispr Mouse with ReDeeM, Batch1, RNA, sample 14 |
| GSM8113082 |
Crispr Mouse with ReDeeM, Batch1, Target Site, sample 14 |
| GSM8113083 |
Crispr Mouse with ReDeeM, Batch1, Cell Hash Site, sample 14 |
| GSM8113084 |
Crispr Mouse with ReDeeM, Batch2, ATAC, (enriched mito included) sample 15 |
| GSM8113086 |
Crispr Mouse with ReDeeM, Batch2, RNA, sample 15 |
| GSM8113087 |
Crispr Mouse with ReDeeM, Batch2, Target Site, sample 15 |
| GSM8113088 |
Crispr Mouse with ReDeeM, Batch2, Cell Hash Site, sample 15 |
| GSM8133910 |
Extended young donors, BMMCs, ATAC(enriched mito included), sample 16 |
| GSM8133911 |
Extended young donors, BMMCs, mRNA-derived cDNA, sample 16 |
| GSM8133912 |
Extended young donors, BMMC, Cell Hash, sample 16 |
| GSM8133913 |
Extended young donors, HSPCs, ATAC(enriched mito included), sample 17 |
| GSM8133914 |
Extended young donors, HSPCs, mRNA-derived cDNA, sample 17 |
| GSM8133915 |
Extended young donors, HSPCs, Cell Hash, sample 17 |
| GSM8133916 |
Extended aged donors, BMMCs_HSPCs, ATAC(enriched mito included), sample 18 |
| GSM8133917 |
Extended aged donors, BMMCs_HSPCs, mRNA-derived cDNA, sample 18 |
| GSM8133918 |
Extended aged donors, BMMCs_HSPCs, Cell Hash, sample 18 |
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| This SuperSeries is composed of the following SubSeries:
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| GSE219014 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Aged 1] |
| GSE219057 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Aged 2] |
| GSE219106 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Young 1] |
| GSE219167 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Young1_T2] |
| GSE219248 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Young2] |
| GSE259284 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Crispr_Mouse_Batch1] |
| GSE259285 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Crispr_Mouse_Batch2] |
| GSE261078 |
Deciphering cell states and genealogies of human hematopoiesis with single-cell multi-omics [Extended donors] |
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| Relations |
| BioProject |
PRJNA906587 |
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