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Status |
Public on Feb 06, 2023 |
Title |
Effect of the gain-of-function mutation of CXCR4 on the molecular identity of murine Skeletal Stromal/Stem Cells (SSC) and OsteoProgenitor Cells (OPC) |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
In order to perform transcriptional analyses of two stromal subsets carrying the gain-of-function mutation of CXCR4, bulk RNA Sequencing (RNA-Seq) was conducted on SSC and OPC sorted from WT (Cxcr4+/+) , heterozygous (Cxcr4+/1013) and homozygous (Cxcr41013/1013) mutant mice for Cxcr4.
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Overall design |
Comparative analysis of gene expression profiling using the RNA-seq data for Cxcr4+/+, Cxcr4+/1013 and Cxcr41013/1013 SSC or OPC
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Contributor(s) |
BALABANIAN K, ABOU NADER Z |
Citation(s) |
37045841 |
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Submission date |
Nov 07, 2022 |
Last update date |
May 11, 2023 |
Contact name |
Zeina Abou Nader |
E-mail(s) |
zeina.abou-nader@inserm.fr
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Organization name |
Institut de Recherche Saint Louis- Hopital Saint Louis
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Street address |
1 AVENUE CLAUDE VELLEFAUX
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City |
Paris |
ZIP/Postal code |
75010 |
Country |
France |
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Platforms (1) |
GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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Samples (17)
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Relations |
BioProject |
PRJNA898991 |