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Status |
Public on Feb 01, 2024 |
Title |
Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
To investigate UPF1 can regulates lncRNA-HEIH transcripts and function of lncRNA-HEIH, we established UPF1 knock out HeLa cell using CRISPR/cas9 system and overexpressed lncRNA-HEIH using plasmids.
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Overall design |
We then performed gene expression profiling analysis using data obtained from RNA-seq of i) WT HeLa cells and UPF1 knock out clone 9 and 41. ii) control and lncRNA-HEIH overexpressed Huh7 cell
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Contributor(s) |
Cha H, Kim M, Jeong S, Ahn N, Ignatova E, Chi S, Kim H, Hwang J |
Citation(s) |
38297160 |
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Submission date |
Oct 26, 2022 |
Last update date |
Mar 13, 2024 |
Contact name |
HyunHo cha |
E-mail(s) |
chahh96@naver.com
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Phone |
82-02-2220-2427
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Organization name |
hanyang university
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Department |
Biomedical Science
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Lab |
Posttranscriptional Gene Regulation Laboratory
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Street address |
222, Wangsimni-ro, Seongdong-gu
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City |
Seoul |
ZIP/Postal code |
04763 |
Country |
South Korea |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (7)
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Relations |
BioProject |
PRJNA894721 |