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| Status |
Public on Feb 01, 2024 |
| Title |
Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
To investigate UPF1 can regulates lncRNA-HEIH transcripts and function of lncRNA-HEIH, we established UPF1 knock out HeLa cell using CRISPR/cas9 system and overexpressed lncRNA-HEIH using plasmids.
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| Overall design |
We then performed gene expression profiling analysis using data obtained from RNA-seq of i) WT HeLa cells and UPF1 knock out clone 9 and 41. ii) control and lncRNA-HEIH overexpressed Huh7 cell
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| Contributor(s) |
Cha H, Kim M, Jeong S, Ahn N, Ignatova E, Chi S, Kim H, Hwang J |
| Citation(s) |
38297160 |
| |
| Submission date |
Oct 26, 2022 |
| Last update date |
Mar 13, 2024 |
| Contact name |
HyunHo cha |
| E-mail(s) |
chahh96@naver.com
|
| Phone |
82-02-2220-2427
|
| Organization name |
hanyang university
|
| Department |
Biomedical Science
|
| Lab |
Posttranscriptional Gene Regulation Laboratory
|
| Street address |
222, Wangsimni-ro, Seongdong-gu
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| City |
Seoul |
| ZIP/Postal code |
04763 |
| Country |
South Korea |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (7)
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| Relations |
| BioProject |
PRJNA894721 |
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