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| Status |
Public on Oct 27, 2022 |
| Title |
Sex differences in RBM20 cardiomyopathy |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this study, we investigated potential sex differences in a Rbm20 knockout mouse model. We used RNA sequencing of bulk RNA from the left ventricle of male and female wildtype and Rbm20 knockout mice.
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| Overall design |
10-week old male and female wildtype and Rbm20 knockout mice were sacrificed, their hearts were harvested, and RNA from the LV was isolated and used for RNA sequencing.
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| Contributor(s) |
van den Hoogenhof MM, Pepin ME |
| Citation(s) |
36367695 |
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| Submission date |
Oct 20, 2022 |
| Last update date |
Jan 26, 2023 |
| Contact name |
Maarten M.G. van den Hoogenhof |
| E-mail(s) |
maarten.vandenhoogenhof@med.uni-heidelberg.de, ho152@uni-heidelberg.de
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| Phone |
+4962215632147
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| Organization name |
Institute of Experimental Cardiology
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| Street address |
In Neuenheimer Feld 669
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| City |
Heidelberg |
| State/province |
(select) |
| ZIP/Postal code |
69120 |
| Country |
Germany |
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| Platforms (1) |
| GPL21103 |
Illumina HiSeq 4000 (Mus musculus) |
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| Samples (40)
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| GSM6659292 |
LV heart tissue, wildtype, female (wt_f_140-1) |
| GSM6659293 |
LV heart tissue, wildtype, female (wt_f_141-1) |
| GSM6659294 |
LV heart tissue, wildtype, female (wt_f_142-1) |
| GSM6659295 |
LV heart tissue, wildtype, female (wt_f_143-1) |
| GSM6659296 |
LV heart tissue, wildtype, female (wt_f_144-1) |
| GSM6659297 |
LV heart tissue, wildtype, male (wt_m_112-1) |
| GSM6659298 |
LV heart tissue, wildtype, male (wt_m_113-1) |
| GSM6659299 |
LV heart tissue, wildtype, male (wt_m_124-1) |
| GSM6659300 |
LV heart tissue, wildtype, male (wt_m_125-1) |
| GSM6659301 |
LV heart tissue, wildtype, male (wt_m_139-1) |
| GSM6659302 |
LV heart tissue, Rbm20 knockout, female (ko_f_150-1) |
| GSM6659303 |
LV heart tissue, Rbm20 knockout, female (ko_f_151-1) |
| GSM6659304 |
LV heart tissue, Rbm20 knockout, female (ko_f_154-1) |
| GSM6659305 |
LV heart tissue, Rbm20 knockout, female (ko_f_155-1) |
| GSM6659306 |
LV heart tissue, Rbm20 knockout, female (ko_f_95-1) |
| GSM6659307 |
LV heart tissue, Rbm20 knockout, male (ko_m_97-1) |
| GSM6659308 |
LV heart tissue, Rbm20 knockout, male (ko_m_106-1) |
| GSM6659309 |
LV heart tissue, Rbm20 knockout, male (ko_m_127-1) |
| GSM6659310 |
LV heart tissue, Rbm20 knockout, male (ko_m_128-1) |
| GSM6659311 |
LV heart tissue, Rbm20 knockout, male (ko_m_130-1) |
| GSM6659312 |
LV heart tissue, wildtype, female (wt_f_140-2) |
| GSM6659313 |
LV heart tissue, wildtype, female (wt_f_141-2) |
| GSM6659314 |
LV heart tissue, wildtype, female (wt_f_142-2) |
| GSM6659315 |
LV heart tissue, wildtype, female (wt_f_143-2) |
| GSM6659316 |
LV heart tissue, wildtype, female (wt_f_144-2) |
| GSM6659317 |
LV heart tissue, wildtype, male (wt_m_112-2) |
| GSM6659318 |
LV heart tissue, wildtype, male (wt_m_113-2) |
| GSM6659319 |
LV heart tissue, wildtype, male (wt_m_124-2) |
| GSM6659320 |
LV heart tissue, wildtype, male (wt_m_125-2) |
| GSM6659321 |
LV heart tissue, wildtype, male (wt_m_139-2) |
| GSM6659322 |
LV heart tissue, Rbm20 knockout, female (ko_f_150-2) |
| GSM6659323 |
LV heart tissue, Rbm20 knockout, female (ko_f_151-2) |
| GSM6659324 |
LV heart tissue, Rbm20 knockout, female (ko_f_154-2) |
| GSM6659325 |
LV heart tissue, Rbm20 knockout, female (ko_f_155-2) |
| GSM6659326 |
LV heart tissue, Rbm20 knockout, female (ko_f_95-2) |
| GSM6659327 |
LV heart tissue, Rbm20 knockout, male (ko_m_97-2) |
| GSM6659328 |
LV heart tissue, Rbm20 knockout, male (ko_m_106-2) |
| GSM6659329 |
LV heart tissue, Rbm20 knockout, male (ko_m_127-2) |
| GSM6659330 |
LV heart tissue, Rbm20 knockout, male (ko_m_128-2) |
| GSM6659331 |
LV heart tissue, Rbm20 knockout, male (ko_m_130-2) |
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| Relations |
| BioProject |
PRJNA892331 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE216147_F_RBM20.KO.v.CON_DESeq2.xlsx |
12.1 Mb |
(ftp)(http) |
XLSX |
| GSE216147_F_RBM20.KO.v.CON_DEXSeqCORRECT.xlsx |
3.3 Mb |
(ftp)(http) |
XLSX |
| GSE216147_M_RBM20.KO.v.CON_DESeq2.xlsx |
10.3 Mb |
(ftp)(http) |
XLSX |
| GSE216147_M_RBM20.KO.v.CON_DEXSeqCORRECT.xlsx |
10.6 Mb |
(ftp)(http) |
XLSX |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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