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| Status |
Public on Mar 01, 2024 |
| Title |
Effects of IL-1b inhibition on the phenotypes of spleen naive CD4+ T (TN) cells. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To analyze the influence of IL-1b on TN cells, RNA-seq analysis was performed on spleen TN cells from mice treated or not treated with IL-1b inhibitors.
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| Overall design |
Comparative gene exprssion profiling analysis of RNA-seq data for total TN cells isolated from speen of mice treated or not treated with anti-IL-1b neutralizing antibodies or MCC950 for 10 consecutive days.
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| Contributor(s) |
Takashi S |
| Citation(s) |
38492221 |
| |
| Submission date |
Oct 14, 2022 |
| Last update date |
Jun 01, 2024 |
| Contact name |
Takashi Sekiya |
| E-mail(s) |
lb-sekiya@hospk.ncgm.go.jp
|
| Organization name |
National Center for Global Health and Medicine
|
| Street address |
1-7-1 Kohnodai
|
| City |
Ichikawa |
| State/province |
Chiba |
| ZIP/Postal code |
272-0827 |
| Country |
Japan |
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| Platforms (1) |
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| Samples (9)
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| GSM6639473 |
Spleen TN cells from untreated mice, rep1 |
| GSM6639474 |
Spleen TN cells from untreated mice, rep2 |
| GSM6639475 |
Spleen TN cells from untreated mice, rep3 |
| GSM6639476 |
Spleen TN cells from anti-IL-1b-treated mice, rep1 |
| GSM6639477 |
Spleen TN cells from anti-IL-1b-treated mice, rep2 |
| GSM6639478 |
Spleen TN cells from anti-IL-1b-treated mice, rep3 |
| GSM6639479 |
Spleen TN cells from MCC950-treated mice, rep1 |
| GSM6639480 |
Spleen TN cells from MCC950-treated mice, rep2 |
| GSM6639481 |
Spleen TN cells from MCC950-treated mice, rep3 |
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| This SubSeries is part of SuperSeries: |
| GSE215778 |
Tonic TCR and IL-1beta signaling mediate phenotypic alterations of naive CD4+ T cells |
|
| Relations |
| BioProject |
PRJNA890602 |
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