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Series GSE215455 Query DataSets for GSE215455
Status Public on Oct 20, 2022
Title JAK2V617F-dependent clonal hematopoiesis drives vascular resident macrophages toward a pathogenic phenotype and promotes dissecting aortic aneurysm
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary In order to understand the mechanisms responsible for lethal JAK2V617F-dependent aortic disease, we performed RNA sequencing in the aorta of 7-week old Jak2V617F HC-EC and control Jak2WT mice
Overall design Bulk aorta RNA-seq analysis from 7-week old mice with a JAK2V617F mutation or their wild-type littermates.
Contributor(s) Al-Rifai R, Ait-Oufella H, Diedisheim M
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Submission date Oct 13, 2022
Last update date Oct 23, 2022
Contact name Hafid Ait-Oufella
Phone +33612011940
Organization name Inserm
Department U970
Street address 56, Rue Leblanc
City Paris
ZIP/Postal code 75015
Country France
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (10)
GSM6637504 aorta_wt_1
GSM6637505 aorta_wt_2
GSM6637506 aorta_wt_3
BioProject PRJNA890296

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE215455_RAW.tar 11.5 Mb (http)(custom) TAR (of RESULTS)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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