 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Jun 02, 2023 |
| Title |
Argonaute 2 associated miRNAs in CA1, CA3 and Dentate Gyrus hippocampal subfields from the rat perforant pathway stimulation (PPS) epilepsy model |
| Organism |
Rattus norvegicus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
MicroRNAs (miRNAs) are short noncoding RNAs that shape the gene expression landscape, including during the pathogenesis of temporal lobe epilepsy (TLE). In order to provide a full catalog of the miRNA changes that happen during experimental TLE, we sequenced Argonaute 2-loaded miRNAs in CA1, CA3 and Dentate Gyrus hippocampal subfields from the rat perforant pathway stimulation (PPS) model at regular intervals between the time of the initial precipitating insult to the establishment of spontaneous recurrent seizures.
|
| |
|
| Overall design |
small RNA sequencing of Ago2-loaded miRNAs from rat perforant pathway stimulation (PPS) model of epilepsy development. Sequenced in timepoints during epileptogenesis and at chronic phase. Each group is in triplicate.
|
| Web link |
https://pubmed.ncbi.nlm.nih.gov/37463203/
|
| |
|
| Contributor(s) |
Veno MT, Kjems J, Henshall DC |
| Citation(s) |
37463203 |
| |
| Submission date |
Sep 28, 2022 |
| Last update date |
Nov 19, 2023 |
| Contact name |
Morten T Veno |
| E-mail(s) |
morten.veno@omiics.com
|
| Phone |
+45 28727107
|
| Organization name |
Omiics ApS
|
| Street address |
Aabogade 15
|
| City |
Aarhus N |
| State/province |
DK |
| ZIP/Postal code |
8200 |
| Country |
Denmark |
| |
|
| Platforms (1) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
|
| Samples (72)
|
| GSM6604542 |
MRP1_CA1_24: Rat, perforant pathway stimulation (PPS), 1 hour, CA1 |
| GSM6604543 |
MRP1_CA1_26: Rat, perforant pathway stimulation (PPS), 1 hour, CA1 |
| GSM6604544 |
MRP1_CA1_36: Rat, perforant pathway stimulation (PPS), 1 hour, CA1 |
| GSM6604545 |
MRP2_CA1_11: Rat, perforant pathway stimulation (PPS), 24 hours, CA1 |
| GSM6604546 |
MRP2_CA1_15: Rat, perforant pathway stimulation (PPS), 24 hours, CA1 |
| GSM6604547 |
MRP2_CA1_16: Rat, perforant pathway stimulation (PPS), 24 hours, CA1 |
| GSM6604548 |
MRP3_CA1_1: Rat, perforant pathway stimulation (PPS), 72 hours, CA1 |
| GSM6604549 |
MRP3_CA1_2: Rat, perforant pathway stimulation (PPS), 72 hours, CA1 |
| GSM6604550 |
MRP3_CA1_3: Rat, perforant pathway stimulation (PPS), 72 hours, CA1 |
| GSM6604551 |
MRP4_CA1_4: Rat, perforant pathway stimulation (PPS), 10 days, CA1 |
| GSM6604552 |
MRP4_CA1_5: Rat, perforant pathway stimulation (PPS), 10 days, CA1 |
| GSM6604553 |
MRP4_CA1_9: Rat, perforant pathway stimulation (PPS), 10 days, CA1 |
| GSM6604554 |
MRP5_CA1_19: Rat, perforant pathway stimulation (PPS), 16 days, CA1 |
| GSM6604555 |
MRP5_CA1_28: Rat, perforant pathway stimulation (PPS), 16 days, CA1 |
| GSM6604556 |
MRP5_CA1_6: Rat, perforant pathway stimulation (PPS), 16 days, CA1 |
| GSM6604557 |
MRP6_CA1_64: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA1 |
| GSM6604558 |
MRP6_CA1_69: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA1 |
| GSM6604559 |
MRP6_CA1_74: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA1 |
| GSM6604560 |
MRP7_CA1_37: Rat, perforant pathway stimulation (PPS), Chronic, CA1 |
| GSM6604561 |
MRP7_CA1_43: Rat, perforant pathway stimulation (PPS), Chronic, CA1 |
| GSM6604562 |
MRP7_CA1_75: Rat, perforant pathway stimulation (PPS), Chronic, CA1 |
| GSM6604563 |
MRP8_CA1_17: Rat, perforant pathway stimulation (PPS), Control, CA1 |
| GSM6604564 |
MRP8_CA1_20: Rat, perforant pathway stimulation (PPS), Control, CA1 |
| GSM6604565 |
MRP8_CA1_31: Rat, perforant pathway stimulation (PPS), Control, CA1 |
| GSM6604566 |
MRP1_CA3_24: Rat, perforant pathway stimulation (PPS), 1 hour, CA3 |
| GSM6604567 |
MRP1_CA3_26: Rat, perforant pathway stimulation (PPS), 1 hour, CA3 |
| GSM6604568 |
MRP1_CA3_36: Rat, perforant pathway stimulation (PPS), 1 hour, CA3 |
| GSM6604569 |
MRP2_CA3_11: Rat, perforant pathway stimulation (PPS), 24 hours, CA3 |
| GSM6604570 |
MRP2_CA3_15: Rat, perforant pathway stimulation (PPS), 24 hours, CA3 |
| GSM6604571 |
MRP2_CA3_16: Rat, perforant pathway stimulation (PPS), 24 hours, CA3 |
| GSM6604572 |
MRP3_CA3_1: Rat, perforant pathway stimulation (PPS), 72 hours, CA3 |
| GSM6604573 |
MRP3_CA3_2: Rat, perforant pathway stimulation (PPS), 72 hours, CA3 |
| GSM6604574 |
MRP3_CA3_3: Rat, perforant pathway stimulation (PPS), 72 hours, CA3 |
| GSM6604575 |
MRP4_CA3_4: Rat, perforant pathway stimulation (PPS), 10 days, CA3 |
| GSM6604576 |
MRP4_CA3_5: Rat, perforant pathway stimulation (PPS), 10 days, CA3 |
| GSM6604577 |
MRP4_CA3_9: Rat, perforant pathway stimulation (PPS), 10 days, CA3 |
| GSM6604578 |
MRP5_CA3_19: Rat, perforant pathway stimulation (PPS), 16 days, CA3 |
| GSM6604579 |
MRP5_CA3_28: Rat, perforant pathway stimulation (PPS), 16 days, CA3 |
| GSM6604580 |
MRP5_CA3_6: Rat, perforant pathway stimulation (PPS), 16 days, CA3 |
| GSM6604581 |
MRP6_CA3_64: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA3 |
| GSM6604582 |
MRP6_CA3_69: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA3 |
| GSM6604583 |
MRP6_CA3_74: Rat, perforant pathway stimulation (PPS), Day of first seizure, CA3 |
| GSM6604584 |
MRP7_CA3_37: Rat, perforant pathway stimulation (PPS), Chronic, CA3 |
| GSM6604585 |
MRP7_CA3_43: Rat, perforant pathway stimulation (PPS), Chronic, CA3 |
| GSM6604586 |
MRP7_CA3_75: Rat, perforant pathway stimulation (PPS), Chronic, CA3 |
| GSM6604587 |
MRP8_CA3_17: Rat, perforant pathway stimulation (PPS), Control, CA3 |
| GSM6604588 |
MRP8_CA3_20: Rat, perforant pathway stimulation (PPS), Control, CA3 |
| GSM6604589 |
MRP8_CA3_31: Rat, perforant pathway stimulation (PPS), Control, CA3 |
| GSM6604590 |
MRP1_DG_24: Rat, perforant pathway stimulation (PPS), 1 hour, DG |
| GSM6604591 |
MRP1_DG_26: Rat, perforant pathway stimulation (PPS), 1 hour, DG |
| GSM6604592 |
MRP1_DG_36: Rat, perforant pathway stimulation (PPS), 1 hour, DG |
| GSM6604593 |
MRP2_DG_11: Rat, perforant pathway stimulation (PPS), 24 hours, DG |
| GSM6604594 |
MRP2_DG_15: Rat, perforant pathway stimulation (PPS), 24 hours, DG |
| GSM6604595 |
MRP2_DG_16: Rat, perforant pathway stimulation (PPS), 24 hours, DG |
| GSM6604596 |
MRP3_DG_1: Rat, perforant pathway stimulation (PPS), 72 hours, DG |
| GSM6604597 |
MRP3_DG_2: Rat, perforant pathway stimulation (PPS), 72 hours, DG |
| GSM6604598 |
MRP3_DG_3: Rat, perforant pathway stimulation (PPS), 72 hours, DG |
| GSM6604599 |
MRP4_DG_4: Rat, perforant pathway stimulation (PPS), 10 days, DG |
| GSM6604600 |
MRP4_DG_5: Rat, perforant pathway stimulation (PPS), 10 days, DG |
| GSM6604601 |
MRP4_DG_9: Rat, perforant pathway stimulation (PPS), 10 days, DG |
| GSM6604602 |
MRP5_DG_19: Rat, perforant pathway stimulation (PPS), 16 days, DG |
| GSM6604603 |
MRP5_DG_28: Rat, perforant pathway stimulation (PPS), 16 days, DG |
| GSM6604604 |
MRP5_DG_6: Rat, perforant pathway stimulation (PPS), 16 days, DG |
| GSM6604605 |
MRP6_DG_64: Rat, perforant pathway stimulation (PPS), Day of first seizure, DG |
| GSM6604606 |
MRP6_DG_69: Rat, perforant pathway stimulation (PPS), Day of first seizure, DG |
| GSM6604607 |
MRP6_DG_74: Rat, perforant pathway stimulation (PPS), Day of first seizure, DG |
| GSM6604608 |
MRP7_DG_37: Rat, perforant pathway stimulation (PPS), Chronic, DG |
| GSM6604609 |
MRP7_DG_43: Rat, perforant pathway stimulation (PPS), Chronic, DG |
| GSM6604610 |
MRP7_DG_75: Rat, perforant pathway stimulation (PPS), Chronic, DG |
| GSM6604611 |
MRP8_DG_17: Rat, perforant pathway stimulation (PPS), Control, DG |
| GSM6604612 |
MRP8_DG_20: Rat, perforant pathway stimulation (PPS), Control, DG |
| GSM6604613 |
MRP8_DG_31: Rat, perforant pathway stimulation (PPS), Control, DG |
|
| Relations |
| BioProject |
PRJNA885062 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE214355_CA1_PPS_miRNA_raw_count.txt.gz |
22.7 Kb |
(ftp)(http) |
TXT |
| GSE214355_CA3_PPS_miRNA_raw_count.txt.gz |
22.9 Kb |
(ftp)(http) |
TXT |
| GSE214355_DG_PPS_miRNA_raw_count.txt.gz |
23.1 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...