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GEO help: Mouse over screen elements for information. |
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Status |
Public on Sep 30, 2022 |
Title |
High-dose glutamine modulates amino acid transport and mediates pancreatic cancer chemosensitivity |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
We performed RNA-seq to investigate gene expression changes in pancreatic cancer cells following gemcitabine with high-dose L-Gln.
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Overall design |
RNA-seq was performed in MIA PaCa-2 cells with biological triplicates under various conditions (gemcitabine 0 or 0.5 uM, and L-Gln; 2 or 40 mM).
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Contributor(s) |
Bhowmick NA, Muranaka H, You S, Cruz-Hernandez CD |
Citation missing |
Has this study been published? Please login to update or notify GEO. |
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Submission date |
Sep 27, 2022 |
Last update date |
Sep 30, 2022 |
Contact name |
Carlos David Cruz |
E-mail(s) |
carlosdavidcruzher@gmail.com
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Phone |
4245273648
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Organization name |
Cedars Sinai
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Department |
SOCC
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Lab |
Bhowmick's Lab
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Street address |
8700 Beverly Boulevard
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City |
Los Angeles |
State/province |
California |
ZIP/Postal code |
90048 |
Country |
USA |
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Platforms (1) |
GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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Samples (12)
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GSM6604242 |
MIA PaCa-2, L-Gln 2mM, Gem 0, 48h [MP2_A_1] |
GSM6604243 |
MIA PaCa-2, L-Gln 2mM, Gem 0, 48h [MP2_A_2] |
GSM6604244 |
MIA PaCa-2, L-Gln 2mM, Gem 0, 48h [MP2_A_3] |
GSM6604245 |
MIA PaCa-2, L-Gln 2mM, Gem 0.5 uM, 48h [MP2_B_1] |
GSM6604246 |
MIA PaCa-2, L-Gln 2mM, Gem 0.5 uM, 48h [MP2_B_2] |
GSM6604247 |
MIA PaCa-2, L-Gln 2mM, Gem 0.5 uM, 48h [MP2_B_3] |
GSM6604248 |
MIA PaCa-2, L-Gln 40mM, Gem 0, 48h [MP2_C_1] |
GSM6604249 |
MIA PaCa-2, L-Gln 40mM, Gem 0, 48h [MP2_C_2] |
GSM6604250 |
MIA PaCa-2, L-Gln 40mM, Gem 0, 48h [MP2_C_3] |
GSM6604251 |
MIA PaCa-2, L-Gln 40mM, Gem 0.5 uM, 48h [MP2_D_1] |
GSM6604252 |
MIA PaCa-2, L-Gln 40mM, Gem 0.5 uM, 48h [MP2_D_2] |
GSM6604253 |
MIA PaCa-2, L-Gln 40mM, Gem 0.5 uM, 48h [MP2_D_3] |
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Relations |
BioProject |
PRJNA884815 |
Supplementary file |
Size |
Download |
File type/resource |
GSE214325_norm.csv.gz |
927.1 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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