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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Aug 30, 2022 |
| Title |
JMJD4 regulates PKM2 degradation of cardiomyocytes and is critical in the development of dilated cardiomyopathy |
| Organisms |
Mus musculus; Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
RNA-Seq results of adult mouse cardiomyocytes with Jmjd4 knockout and neonatal rat cardiomyocytes with Jmjd4 knockdown.
To investigate the role of Jmjd4 in dilated cardiomyopathy, we performed gene expression profiling with RNA-Seq results from heart samples of MCM+ Jmjd4f/f and control Jmjd4f/f mice, as well as neonatal rat ventricuar cardiomyocytes (NRVCs) treated with si-Jmjd4 and si-NC control.
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| Overall design |
RNA-Seq analysis of Jmjd4 cKO mice heart tissue and Jmjd4 knock down NRVCs
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| Contributor(s) |
Tang Y, Zhang H, Wei K |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Aug 24, 2022 |
| Last update date |
Aug 30, 2022 |
| Contact name |
yansong tang |
| E-mail(s) |
yansongtang0@gmail.com
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| Organization name |
Tongji University
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| Street address |
Siping Road
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| City |
Shanghai |
| ZIP/Postal code |
200092 |
| Country |
China |
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| Platforms (2) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
| GPL25947 |
Illumina NovaSeq 6000 (Rattus norvegicus) |
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| Samples (12)
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| GSM6506096 |
Jmjd4, cKO, rep1 |
| GSM6506097 |
Jmjd4, cKO, rep2 |
| GSM6506098 |
Jmjd4, cKO, rep3 |
| GSM6506099 |
NRVC, si-NC, rep1 |
| GSM6506100 |
NRVC, si-NC, rep2 |
| GSM6506101 |
NRVC, si-NC, rep3 |
| GSM6506102 |
NRVC, si-Jmjd4, rep1 |
| GSM6506103 |
NRVC, si-Jmjd4, rep2 |
| GSM6506104 |
NRVC, si-Jmjd4, rep3 |
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| Relations |
| BioProject |
PRJNA873050 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE211955_NRVC_si-Jmjd4.csv.gz |
306.1 Kb |
(ftp)(http) |
CSV |
| GSE211955_mouse_CKO.csv.gz |
432.5 Kb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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