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| Status |
Public on Aug 21, 2022 |
| Title |
Mouse feeder-free alveolar organoids treated by bleomycin |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To investigate the direct effect of bleomycin on alveolar epithelium, feeder-free mouse alveolar organoids were treated by bleomycin (100μM) for 48 hours in vitro and then analyzed.
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| |
|
| Overall design |
Alveolar organoids were made from primary alveolar epithelial cell type 2 (GFP+ in FACS) isolated from tamoxifen-treated Sftpc-creERT2; Rosa26-mTmG mice (male, 9wks).
Comparative gene expression profiling analysis of RNA-seq data between bleomycin-treated and untreated mouse alveolar organoids.
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| Web link |
https://www.nature.com/articles/s41467-023-40617-y
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| |
|
| Contributor(s) |
Enomoto Y |
| Citation(s) |
37653024 |
| |
| Submission date |
Aug 18, 2022 |
| Last update date |
Sep 01, 2023 |
| Contact name |
Yasunori Enomoto |
| E-mail(s) |
enomotoy@hama-med.ac.jp
|
| Phone |
81534352223
|
| Organization name |
Hamamatsu University School of Medicine
|
| Department |
Department of Regenerative and Infectious Pathology
|
| Street address |
1-20-1 Handayama
|
| City |
Hamamatsu |
| State/province |
Shizuoka |
| ZIP/Postal code |
431-3192 |
| Country |
Japan |
| |
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| Platforms (1) |
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| Samples (8)
|
| GSM6475186 |
Mouse alveolar organoids, CTRL48h, rep1 |
| GSM6475187 |
Mouse alveolar organoids, CTRL48h, rep2 |
| GSM6475188 |
Mouse alveolar organoids, CTRL48h, rep3 |
| GSM6475189 |
Mouse alveolar organoids, CTRL48h, rep4 |
| GSM6475190 |
Mouse alveolar organoids, BLM48h, rep1 |
| GSM6475191 |
Mouse alveolar organoids, BLM48h, rep2 |
| GSM6475192 |
Mouse alveolar organoids, BLM48h, rep3 |
| GSM6475193 |
Mouse alveolar organoids, BLM48h, rep4 |
|
| Relations |
| BioProject |
PRJNA870738 |
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