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| Status |
Public on Aug 09, 2022 |
| Title |
Next Generation Sequencing Facilitates Quantitative Analysis of Mock/ZIKV infected Guinea Pig Lung Transcriptomes |
| Organism |
Cavia porcellus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Whether Zika virus (ZIKV) could be transmitted via aerosol routes remains unknown. In this study, we demonstrated that aerosolized ZIKV is fully infectious in vitro and in vivo.Transcriptome analysis further revealed that genes expression related to viral process, biological regulation and immune system response were significantly changed.
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| |
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| Overall design |
Guinea pigs before or after infection (1,3 or 7 dpi) were used for RNA-seq.
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| |
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| Contributor(s) |
Qiu H, Li R |
| Citation(s) |
36069671 |
| |
| Submission date |
Aug 02, 2022 |
| Last update date |
Oct 28, 2022 |
| Contact name |
Rui-Ting Li |
| Organization name |
Beijing Institute of Microbiology and Epidemiology
|
| Department |
State Key Laboratory of Pathogen and Biosecurity
|
| Street address |
No.20 Dongda Street, Fengtai District
|
| City |
Beijing |
| State/province |
Beijing |
| ZIP/Postal code |
100071 |
| Country |
China |
| |
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| Platforms (1) |
| GPL28437 |
Illumina NovaSeq 6000 (Cavia porcellus) |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA865378 |
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