|
| Status |
Public on Jan 11, 2023 |
| Title |
Effect of NEAT1 modulation on antiviral immune response |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Reduction of NEAT1 transcript associated with Cell type-specific differential expression. The Knockdown of NEAT1 in Huh7 cells modulated antiviral response and dengue virus replication via the RIG-I pathway.
We then performed gene expression profiling analysis using data obtained from RNA-seq of 4 different cells at two time points.
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| |
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for NEAT1 knock down and wild type Huh7 cells infected with Dengue virus2.
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| |
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| Contributor(s) |
Banerjee A, Saini J, Vrati S, Pandey AD |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jul 26, 2022 |
| Last update date |
Jan 11, 2023 |
| Contact name |
Abhay Deep Pandey |
| E-mail(s) |
abhay.deep@rcb.res.in
|
| Phone |
9717206143
|
| Organization name |
Regional Centre for Biotechnology
|
| Department |
Virology
|
| Lab |
Molecular Virology
|
| Street address |
3rd Milestone, Faridabad-Gurgaon Expressway
|
| City |
Faridabad |
| ZIP/Postal code |
121001 |
| Country |
India |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (6)
|
| GSM6394937 |
Huh7 cells, AS0_Control, 24hpi [Sample 7] |
| GSM6394938 |
Huh7 cells, ASO_Control, 24hpi [Sample 8] |
| GSM6394939 |
Huh7 cells, ASO_Control, 24hpi [Sample 9] |
| GSM6394940 |
Huh7 cells, ASO_NEAT1, 24hpi [Sample 10] |
| GSM6394941 |
Huh7 cells, ASO_NEAT1, 24hpi [Sample 11] |
| GSM6394942 |
Huh7 cells, ASO_NEAT1, 24hpi [Sample 12] |
|
| Relations |
| BioProject |
PRJNA862359 |
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