|
| Status |
Public on Apr 06, 2023 |
| Title |
Glis3 regulates the expression of thyroid hormone synthetic genes in coordination with other thyroid transcription factors |
| Organisms |
Mus musculus; Rattus norvegicus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Comparison of cistromes from PAX8, NKX2.1, and FOXE1 ChIP-Seq analysis using mouse thyroid gland and rat thyrocyte PCCl3 cells revealed that there is a significant overlap between GLIS3 binding regions and those of PAX8, NKX2.1, and FOXE1 in genes associated with thyroid hormone biosynthesis.
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| |
|
| Overall design |
ChIP-seq for transcription factors PAX8, NKX2.1, GLIS3, and FOXE1 and histone modifications H3K27me3 and H3K4me3.
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| |
|
| Contributor(s) |
Jetten AM, Kang HS, Grimm SA |
| Citation(s) |
36793061 |
| |
| Submission date |
Jul 08, 2022 |
| Last update date |
Jul 06, 2023 |
| Contact name |
Hong Soon Kang |
| E-mail(s) |
kang1@niehs.nih.gov
|
| Phone |
984-287-3921
|
| Organization name |
NIH/NIEHS
|
| Department |
IIDL
|
| Lab |
Cell Biology Group
|
| Street address |
111 T.W. Alexander Dr.
|
| City |
Research Triangle Park |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
|
| Platforms (4)
|
| GPL16417 |
Illumina MiSeq (Mus musculus) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
| GPL20084 |
Illumina NextSeq 500 (Rattus norvegicus) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
|
| Samples (21)
|
|
| Relations |
| BioProject |
PRJNA857053 |
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