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| Status |
Public on Jul 31, 2024 |
| Title |
Regulation of blood-brain barrier by astrocyte through mitochondrial transfer |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
The subset of astrocytes that express Dmp1 were considered to wrap around blood vessels. We used scRNA-seq to investigate the mobility of mitochondria from astrocytesDMP1.
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| Overall design |
Brain single cells with mito-COX8Dendra2 fluorescence from Dmp1Cre-COX8Dendra2 mice were enriched by Fluorescence-activated cell sorting (FACS) according to the presence of Dendra2 signal and analyzed using scRNAseq.
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| Contributor(s) |
Gao J, Liu D |
| Citation(s) |
38941455 |
| |
| Submission date |
Jun 08, 2022 |
| Last update date |
Aug 01, 2024 |
| Contact name |
Junjie Gao |
| E-mail(s) |
Junjie.gao@shsmu.edu.cn
|
| Phone |
+8615067175608
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| Organization name |
Shanghai Jiao Tong University Affiliated Shanghai Sixth People’s Hospital
|
| Street address |
600 Yishan Road
|
| City |
Shanghai |
| ZIP/Postal code |
200233 |
| Country |
China |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA847154 |
