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| Status |
Public on Aug 15, 2010 |
| Title |
Tumor-derived Jagged1- and Notch-dependent transcription changes in MC3T3-E1 osteoblasts |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Transcriptional profiling of MC3T3-E1 osteoblasts that were flow cytometry-separated from cocultures with control or Jagged1-overexpressing tumor cells and treated with either DMSO control or 1μM MRK-003 (gamma-secretase inhibitor).
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| |
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| Overall design |
One cell line (MC3T3-E1) cells: four different experimental conditions: cultured with (1) control tumor cells + DMSO; (2) Jagged1-overexpressing tumor cells + DMSO; (3) control tumor cells + MRK-003; (4) Jagged1-overexpressing tumor cells + MRK-003. Each experiment has two biological replicates. Total, 8 samples.
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| |
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| Contributor(s) |
Sethi N |
| Citation(s) |
21295524 |
| Submission date |
Feb 24, 2010 |
| Last update date |
May 10, 2018 |
| Contact name |
Yibin Kang |
| E-mail(s) |
ykang@princeton.edu
|
| Phone |
609-258-9120
|
| Organization name |
Princeton University
|
| Department |
Molecular Biology
|
| Street address |
LTL 254, Washington Road
|
| City |
Princeton |
| State/province |
NJ |
| ZIP/Postal code |
08544 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA125241 |
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