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| Status |
Public on May 01, 2024 |
| Title |
Accumulating Oxidative DNA Damage in Reconstituting T-cells is Associated with Disease Relapse and Inferior Survival Following Allo-SCT [RNAseq in vitro] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Oxidative T-cell DNA damage impacts GVL
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| Overall design |
Comparative gene expression profiling analysis of RNA-seq data for human T-cells treated with H2O2 to induce oxidative damage to untreated controls (5 donors)
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| Contributor(s) |
Karl F, Liang C, Böttcher-Loschinski R, Mougiakakos D |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
May 25, 2022 |
| Last update date |
May 01, 2024 |
| Contact name |
Chunguang Liang |
| E-mail(s) |
liang@biozentrum.uni-wuerzburg.de
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| Phone |
09313184561
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| Organization name |
Biozentrum
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| Department |
Bioinformatics
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| Lab |
Dr. Chunguang Liang
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| Street address |
Bioinformatik, Biozentrum, Uni Würzburg, Am Hubland
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| City |
Würzburg 97074 |
| State/province |
Bayern |
| ZIP/Postal code |
97074 |
| Country |
Germany |
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| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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| Samples (10)
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| GSM6191283 |
T-cells of healthy donors, control, 72h stimulation, donor 1 [Ctrl.K374] |
| GSM6191284 |
T-cells of healthy donors, 72h stimulation + H2O2 treatment, donor 1 [H2O2.K374] |
| GSM6191285 |
T-cells of healthy donors, control, 72h stimulation, donor 2 [Ctrl.K375] |
| GSM6191286 |
T-cells of healthy donors, 72h stimulation + H2O2 treatment, donor 2 [H2O2.K375] |
| GSM6191287 |
T-cells of healthy donors, control, 72h stimulation, donor 3 [Ctrl.K379] |
| GSM6191288 |
T-cells of healthy donors, 72h stimulation + H2O2 treatment, donor 3 [H2O2.K379] |
| GSM6191289 |
T-cells of healthy donors, control, 72h stimulation, donor 4 [Ctrl.K384] |
| GSM6191290 |
T-cells of healthy donors, 72h stimulation + H2O2 treatment, donor 4 [H2O2.K384] |
| GSM6191291 |
T-cells of healthy donors, control, 72h stimulation, donor 5 [Ctrl.K392] |
| GSM6191292 |
T-cells of healthy donors, 72h stimulation + H2O2 treatment, donor 5 [H2O2.K392] |
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| This SubSeries is part of SuperSeries: |
| GSE204783 |
Accumulating Oxidative DNA Damage in Reconstituting T-cells is Associated with Disease Relapse and Inferior Survival Following Allo-SCT |
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| Relations |
| BioProject |
PRJNA842335 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE204781_invitro_normalized_counts.csv.gz |
1.0 Mb |
(ftp)(http) |
CSV |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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