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| Status |
Public on Aug 03, 2022 |
| Title |
Dynamic changes in peripheral blood monocytes early after anti-PD-1 therapy predict clinical outcomes in hepatocellular carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
We aimed to identify peripheral blood biomarkers that predict the response of advanced HCC to anti-PD-1 therapy.
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| Overall design |
Classical monocytes (CD11b+CD3−CD19−CD14+CD16− cells) were sorted from PBMCs collected at day0 and day7 from four patients with DCB and four patients with NDB.
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| Contributor(s) |
Jeon SH, Lee YJ, Kim H, Nam H, Ryoo B, Park S, Yoo C, Shin E |
| Citation(s) |
35902399 |
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| Submission date |
May 03, 2022 |
| Last update date |
Aug 03, 2022 |
| Contact name |
Seung Hyuck Jeon |
| E-mail(s) |
jeonseunghyuck@gmail.com
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| Organization name |
Korea Advanced Institute of Science and Technology
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| Street address |
291 Daehak-ro, Yuseong-gu
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| City |
Daejeon |
| ZIP/Postal code |
34141 |
| Country |
South Korea |
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| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
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| Samples (16)
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| GSM6098538 |
HCC#08, classical monocytes, Day7, DCB |
| GSM6098539 |
HCC#37, classical monocytes, Day0, DCB |
| GSM6098540 |
HCC#37, classical monocytes, Day7, DCB |
| GSM6098541 |
HCC#48, classical monocytes, Day0, DCB |
| GSM6098542 |
HCC#48, classical monocytes, Day7, DCB |
| GSM6098543 |
HCC#03, classical monocytes, Day0, NDB |
| GSM6098544 |
HCC#03, classical monocytes, Day7, NDB |
| GSM6098545 |
HCC#36, classical monocytes, Day0, NDB |
| GSM6098546 |
HCC#36, classical monocytes, Day7, NDB |
| GSM6098547 |
HCC#50, classical monocytes, Day0, NDB |
| GSM6098548 |
HCC#50, classical monocytes, Day7, NDB |
| GSM6098549 |
HCC#51, classical monocytes, Day0, NDB |
| GSM6098550 |
HCC#51, classical monocytes, Day7, NDB |
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| Relations |
| BioProject |
PRJNA834794 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE202145_Processed_data_log2_normalized.txt.gz |
1013.9 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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