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| Status |
Public on Apr 25, 2022 |
| Title |
Skeletal muscle unloading affects muscle progenitor cells functional activity |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In this work we employed classic skeletal muscle unloading rat model to determine how hindlimb suspension (HS) affects functional activity of skeletal muscle progenitor cells (SMPC). We have purified SMPC from m. soleus from control rats and after 1, 3, 7 and 14 days of exposure (HS1, HS3, HS7, HS14).
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| Overall design |
Libraries were prepared with TruSeq Stranded mRNA kit, samples were RNA-sequenced on Illumina NextSeq 2000, read length 51 bp.
Project was supported by RSF grant №20-75-10080.
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| Web link |
https://doi.org/10.3390/ijms23169150
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| Contributor(s) |
Komarova MY, Ivanova OA, Dmitrieva RI, Shenkman BS, Vilchinskaya NA |
| Citation |
Komorova, M.Y., Rozhkov, S.V., Ivanova, O.A., Turtikova, O.V., Mirzoev, T.M., Dmitrieva, R.I., Shenkman, B.S., Vilchinskaya, N.A. Cultured Myoblasts Derived from Rat Soleus Muscle Show Altered Regulation of Proliferation and Myogenesis during the Course of Mechanical Unloading. Int. J. Mol. Sci. 2022, 23(16), 9150.
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| Submission date |
Apr 22, 2022 |
| Last update date |
Aug 16, 2022 |
| Contact name |
Margarita Sorokina |
| E-mail(s) |
komarovamy96@yandex.ru, sorokinamy96@yandex.ru
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| Organization name |
Almazov National Medical Research Centre
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| Street address |
Akkuratova 2
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| City |
Saint-Petersburg |
| ZIP/Postal code |
197341, 123007 |
| Country |
Russia |
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| Platforms (1) |
| GPL32190 |
NextSeq 2000 (Rattus norvegicus) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA830718 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE201281_Raw_counts_table.txt.gz |
420.0 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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