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Series GSE200177 Query DataSets for GSE200177
Status Public on Mar 28, 2024
Title Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function [ChIP-Seq]
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We investigated the role of Ikaros in regulatory Tcell identity and function during stimulation using RNA-seq, ATAC-seq, and H3K27ac/Foxp3/Ikzf1 ChIP-seq
 
Overall design We performed ATAC-seq, RNA-seq, and ChIPseq against H3K27ac, Foxp3, and Ikzf1 on mouse ex vivo Tregs isolated from spleens
 
Contributor(s) Pahl MC, Thomas R, Wells AD
Citation(s) 38655862
Submission date Apr 05, 2022
Last update date May 10, 2024
Contact name Matthew C Pahl
E-mail(s) pahlm@email.chop.edu
Phone 5704282303
Organization name Children's Hospital of Philadelphia
Department Center for Spatial and Functional Genomics
Lab Struan Grant and Andrew Wells
Street address 3615 Civic Center Blvd
City Philadelphia
State/province PA
ZIP/Postal code 19104
Country USA
 
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (48)
GSM6019848 Treg Ikzf1 conditional knockout ex vivo 1 Foxp3_chip
GSM6019849 Treg Ikzf1 conditional knockout ex vivo 2 Foxp3_chip
GSM6019850 Treg Ikzf1 conditional knockout ex vivo 3 Foxp3_chip
This SubSeries is part of SuperSeries:
GSE200179 Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
Relations
BioProject PRJNA823555

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE200177_RAW.tar 4.5 Gb (http)(custom) TAR (of BIGWIG)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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