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Series GSE200153 Query DataSets for GSE200153
Status Public on May 05, 2022
Title Sex-Specific Differences in MicroRNA Expression during Human Fetal Lung Development
Organism Homo sapiens
Experiment type Non-coding RNA profiling by high throughput sequencing
Summary Our study demonstrates differential expression of numerous autosomal miRNAs between the male and female developing human lung. Additionally, the expression of some miRNAs are modified by age across the pseudoglandular stage in a sex-specific way. Some of these differences in miRNA expression may impact susceptibility to pulmonary disease later in life. Our results suggest that sex-specific miRNA expression during human lung development may be a potential mechanism to explain sex-specific differences in lung development and may impact subsequent disease susceptibility
 
Overall design Identifing sex differences in miRNA expression profiles of human fetal lung tissue after controling for smoke exposure, age, and technicial effects.
 
Contributor(s) Lin NW, Liu C, Yang IV, Maier LA, DeMeo DL, Ye S, Cruse MH, Smith V, Vyhlidal CA, Kechris K, Sharma S, Wood C
Citation(s) 35480332
Submission date Apr 04, 2022
Last update date May 05, 2022
Contact name Sunita Sharma
Organization name University of Colorado Hospital
Department Medicine-Pulmonary Sciences & Critical Care
Street address 13199 East Montview Blvd
City Aurora
ZIP/Postal code 80045
Country USA
 
Platforms (1)
GPL16791 Illumina HiSeq 2500 (Homo sapiens)
Samples (298)
GSM6015759 fetal lung tissue, Sample1
GSM6015760 fetal lung tissue, Sample10
GSM6015761 fetal lung tissue, Sample100
Relations
BioProject PRJNA823352

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE200153_miRNA_counts.tsv.gz 337.9 Kb (ftp)(http) TSV
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