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| Status |
Public on Aug 02, 2022 |
| Title |
A New Gene Set Identifies Senescent Cells and Predicts Senescence Associated Pathways Across Tissues |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Young (6-12 months old) INK-ATTAC mice were untreated. Old (20 months old) mice were treated with either Veh or AP (twice weekly, beginning at 20 months, for a total of 4 months). Centrifuged tibial diaphyses were harvested.
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| Overall design |
INK-ATTAC mice (6-12 months=young) were compared to INK-ATTAC mice (20 months=old), treated with either Vehicle or 10 mg of AP20187 per kg body mass [drug/body mass]) twice weekly beginning at 20 months of age for a total of 4 months.
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| Contributor(s) |
Saul D, Farr JN, Khosla S |
| Citation(s) |
35974106 |
| BioProject |
PRJNA818333 |
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| Submission date |
Mar 27, 2022 |
| Last update date |
Nov 01, 2022 |
| Contact name |
Sundeep Khosla |
| Organization name |
Mayo Clinic
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| Department |
Endocrinology Research
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| Street address |
200 1st St SW
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| City |
Rochester |
| State/province |
MN |
| ZIP/Postal code |
55906 |
| Country |
USA |
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| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (41)
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