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| Status |
Public on Apr 19, 2024 |
| Title |
Tight Junction Claudins-associated vascular heterogeneity determines organotypic metastasis |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
To identify the underlying mechanisms associated with lung and kidney fibrosis inducing lung metastasis, we evaluated global transcriptomic changes in healthy lung, fibrotic lung fibrosis, and lung from mice with kidney fibrosis.
Results provide information on the vascular remodeling of the lungs with organ fibrosis. Lung fibrosis is induced with intratracheal bleomycin administration. Kidney fibrosis is induced by unilateral ureter obstruction (UUO).
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| Overall design |
Total RNA isolated from healthy kidney, healthy lung, fibrotic kidney, fibrotic lung, and lung from mice with kidney fibrosis
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| Contributor(s) |
LeBleu V, Miyake T |
| Citation missing |
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| |
| Submission date |
Mar 22, 2022 |
| Last update date |
Apr 19, 2024 |
| Contact name |
Kalluri Lab |
| E-mail(s) |
kallurilab_submissions@mdanderson.org
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| Organization name |
UT MD Anderson Cancer Center
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| Street address |
1901 East Rd
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| City |
Houston |
| State/province |
Texas |
| ZIP/Postal code |
77054 |
| Country |
USA |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (15)
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| Relations |
| BioProject |
PRJNA818702 |
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