|
| Status |
Public on Jul 04, 2022 |
| Title |
Transcriptomic profiling of compensated and decompensated human right ventricles |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
In order to better understand the molecular mechanisms underlying right ventricular failure in human PAH, a RNA sequencing analysis was performed in RV tissues obtained from subjects clinically categorized as compensated RV (n=11), decompensated RV (n=7) and donor controls (n=14). The study unveils a plethora of factors dysregulated in the RV of PAH patients, which opens new perspectives for translational research.
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| |
|
| Overall design |
mRNA profiles for control, compensated and decompensated human right ventricle
|
| |
|
| Contributor(s) |
Boucherat O, Potus F, Bonnet S |
| Citation(s) |
38132114 |
| |
| Submission date |
Mar 14, 2022 |
| Last update date |
Jan 03, 2024 |
| Contact name |
Olivier Boucherat |
| E-mail(s) |
olivier.boucherat@criucpq.ulaval.ca
|
| Organization name |
Laval University
|
| Street address |
2325 Rue de l'Université
|
| City |
Quebec City |
| State/province |
Quebec |
| ZIP/Postal code |
G1V 0A6 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
| Samples (32)
|
|
| Relations |
| BioProject |
PRJNA816161 |
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