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| Status |
Public on Aug 15, 2022 |
| Title |
HSF1 activates ANXA11-mediated glutamine metabolism by super enhancer long non-coding RNA LINC00857 in colorectal cancer [array] |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
Non-coding RNA profiling by array
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| Summary |
We shed light on a closely cooperative machinery between HSF1 and super enhancer for the first time in CRC. HSF1 could stimulate super enhancer activity by the enrichment of acetyltransferase P300 to LINC00857 promoter region, contributing to LINC00857 transcription.
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| Overall design |
After knocking down HSF1 via 2 specific siRNA, total lncRNA expression profiles was acquired. HCT116 cell was used to acquire expression profiles of a total of 60495 lncRNA after HSF1 knockdown.
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| Contributor(s) |
Li J |
| Citation(s) |
36010849 |
| |
| Submission date |
Mar 09, 2022 |
| Last update date |
Aug 31, 2022 |
| Contact name |
Jiaqiu Li |
| E-mail(s) |
lijq@wfmc.edu.cn
|
| Organization name |
weifang medical university
|
| Street address |
No. 2428, Yuhe Road, Kuiwen District
|
| City |
Weifang City |
| State/province |
省/直辖市 |
| ZIP/Postal code |
261000 |
| Country |
China |
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| Platforms (1) |
| GPL26963 |
Agilent-085982 Arraystar human lncRNA V5 microarray |
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| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE198225 |
HSF1 activates ANXA11-mediated glutamine metabolism by super enhancer long non-coding RNA LINC00857 in colorectal cancer. |
|
| Relations |
| BioProject |
PRJNA814243 |
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