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Series GSE197442 Query DataSets for GSE197442
Status Public on Oct 03, 2022
Title Effects of propranolol exposure to Pimephales promelas (fathead minnow) larva across age and duration
Organism Pimephales promelas
Experiment type Expression profiling by high throughput sequencing
Summary Given that larval fish stages provide opportunities for development of stressor-selective screening level tests, this work aimed to investigate the optimal age of fathead minnow larva and duration of exposure for the pharmaceutical, propranolol, found in the environment. Differentially expressed genes were studied as well as gene set enrichment analysis.
 
Overall design mRNA reads from fathead minnow (FHM) larvae (4 days; 5 days; 6 days post fertilization) were exposed for 6, 24, and 48 h to two concentrations of propranolol (0.66 and 3.3 mg/l). RNASeq reads were mapped against 47K known FHM mRNA transcripts
 
Contributor(s) Toth GP, Bencic D, Martinson J, Flick R, Lattier D, Biales A
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Submission date Feb 25, 2022
Last update date Oct 03, 2022
Contact name Gregory Peter Toth
E-mail(s) toth.greg@epa.gov, gregtoth130@gmail.com
Phone 513-607-1602
Organization name USEPA/ORD
Department CCTE
Lab GLTED/MIB
Street address 26 W ML King Jr. Dr.
City Cincinnati
State/province OH
ZIP/Postal code 45267
Country USA
 
Platforms (1)
GPL25572 Illumina HiSeq 4000 (Pimephales promelas)
Samples (270)
GSM5917432 4D_6H_Control [A1-1]
GSM5917433 4D_6H_Control [A1-2]
GSM5917434 4D_6H_Control [A1-4]
Relations
BioProject PRJNA810355

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE197442_Prop_Xlist2.txt.gz 11.8 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

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