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| Status |
Public on Feb 18, 2022 |
| Title |
Paternal high-fat diet altered sperm 5'tsRNA-Gly-GCC is associated with enhanced gluconeogenesis in the offspring |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
In this study, we aimed to find out how the sperm tsRNA involved in paternal high-fat diet induced abnormal gluconeogenesis of F1 offspring, and explore the underlying molecular mechanism of its regulation.
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| Overall design |
We performed small RNA sequencing to obtain a profile of small RNA in spermatozoa from the CD-F0 and HFD-F0 groups
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| Contributor(s) |
Wang B, Xia L, Zhu D, Zeng H, wei B, Lu L, Li W, Shi Y, Liu J, Zhang Y, Sun M |
| Citation(s) |
35480893 |
| |
| Submission date |
Feb 16, 2022 |
| Last update date |
May 05, 2022 |
| Contact name |
Yunfang Zhang |
| E-mail(s) |
zhangyunfang@tongji.edu.cn
|
| Organization name |
Tongji University
|
| Department |
Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology
|
| Street address |
1239 Siping Road
|
| City |
Shanghai |
| ZIP/Postal code |
200092 |
| Country |
China |
| |
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| Platforms (1) |
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| Samples (10)
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| Relations |
| BioProject |
PRJNA807657 |
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