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| Status |
Public on Apr 19, 2023 |
| Title |
Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging III |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To gain insight into the mechanisms by which exercise affects hematopoietic stem cells, we subjected young and old mice to aerobic exercise and performed single cell transcriptome analysis of hematopoietic progenitors in the bone marrow of these animals.
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| |
|
| Overall design |
Hematopoietic progenitors were isolated from the bone marrow of exercised or control young (4-month old) and old (22-month old) mice by FACS and processed for single cell RNA-seq.
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| Web link |
https://doi.org/10.1016/j.stem.2023.03.016
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| |
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| Contributor(s) |
Liu L, Rando T |
| Citation(s) |
37080206, 37118510 |
| |
| Submission date |
Feb 08, 2022 |
| Last update date |
Aug 02, 2023 |
| Contact name |
Ling Liu |
| E-mail(s) |
lingliu@stanford.edu
|
| Organization name |
Stanford University
|
| Street address |
300 Pasteur Drive
|
| City |
Palo Alto |
| ZIP/Postal code |
94306 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (15)
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| This SubSeries is part of SuperSeries: |
| GSE196364 |
Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging |
|
| Relations |
| BioProject |
PRJNA804519 |
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