|
| Status |
Public on Jan 31, 2022 |
| Title |
Microbiota-derived pentanoate promotes differentiation of regulatory T cells via enhancing iron uptake in the intestine [FeSO4_treated_Treg] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Iron deficiencies are the most common non-enteric syndromes observed in patients with inflammatory bowel diseases (IBD), yet little is known how iron deficiencies impact immune tolerance in the intestine. The goal of this study is to illuminate role of iron in colonic Treg homeostasis regulation.
|
| |
|
| Overall design |
mRNA profiles in iTreg cells treated with FeSO4 or Mock
|
| |
|
| Contributor(s) |
Chang X, Zhu L, Li G |
| Citation(s) |
37188703 |
| |
| Submission date |
Jan 28, 2022 |
| Last update date |
May 16, 2023 |
| Contact name |
Xing Chang |
| E-mail(s) |
changxing@westlake.edu.cn
|
| Phone |
057187920973
|
| Organization name |
Westlake University
|
| Department |
School of Life Sciences
|
| Lab |
Immune Regulation and Human Diseases
|
| Street address |
No.18 Shilongshan Road Cloud Town
|
| City |
Xihu District, Hangzhou |
| State/province |
Zhejiang |
| ZIP/Postal code |
310024 |
| Country |
China |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (4)
|
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| This SubSeries is part of SuperSeries: |
| GSE195607 |
Microbiota-derived pentanoate promotes differentiation of regulatory T cells via enhancing iron uptake in the intestine. |
|
| Relations |
| BioProject |
PRJNA801478 |
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