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| Status |
Public on Jul 12, 2022 |
| Title |
Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in a Mouse Cerebral Aneurysm Model |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Cerebral aneurysms were induced in adult male mice using an elastase model. Single-cell RNA sequencing was then performed on circle of Willis samples obtained at 14 days post-aneurysm induction.
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| Overall design |
Single-cell suspension from surgically isolated circle of Willis arteries from sham, animals that formed cerebral aneurysms and animals that had ruptured aneurysms were subjected to scRNA-seq.
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| Contributor(s) |
Martinez A, Tortelote G, Dumont A |
| Citation(s) |
35770669, 39061841 |
| |
| Submission date |
Jan 12, 2022 |
| Last update date |
Aug 16, 2024 |
| Contact name |
Alejandra Martinez Lege |
| E-mail(s) |
amarti8@tulane.edu
|
| Phone |
5049887608
|
| Organization name |
Tulane University
|
| Department |
Neurosurgery
|
| Street address |
1430 Tulane Ave
|
| City |
New Orleans |
| State/province |
United States |
| ZIP/Postal code |
70112 |
| Country |
USA |
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| Platforms (1) |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA796555 |
