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| Status |
Public on Jan 11, 2023 |
| Title |
Type 2 immune polarization is associated with cardiopulmonary disease in preterm infants |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
In order to explore the cell types involved in a murine model of bronchopulmonary dysplasia, we performed single-cell RNA-seq on lungs from 5 day old mice exposed to inflammation and hyperoxia.
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| Overall design |
Endothelial, epithelial and immune cells were obtained by flow-sorting of lung cells from pups subjected to the murine BPD model (inflammation + hyperoxia) for 5d, and subjected to single cell-sequencing. N=4 per group (Air, Hyperoxia)
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| Contributor(s) |
Bui C, Sun YB, Schroeder J, Nold M |
| Citation(s) |
35385341 |
| |
| Submission date |
Jan 06, 2022 |
| Last update date |
Jan 12, 2023 |
| Contact name |
Jan Schroeder |
| E-mail(s) |
jan.schroeder@monash.edu
|
| Phone |
0433419028
|
| Organization name |
Monash University
|
| Department |
Anatomy & Developmental Biology
|
| Lab |
Epigenetics & Reprogramming
|
| Street address |
Building 75 Innovation Walk
|
| City |
Clayton |
| State/province |
VIC |
| ZIP/Postal code |
3168 |
| Country |
Australia |
| |
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| Platforms (1) |
| GPL24247 |
Illumina NovaSeq 6000 (Mus musculus) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA795251 |
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